MEFV anticorps (AA 2-29)
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- Antigène Voir toutes MEFV Anticorps
- MEFV (Mediterranean Fever (MEFV))
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Épitope
- AA 2-29
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp MEFV est non-conjugé
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Application
- Western Blotting (WB), Immunoprecipitation (IP)
- Specificité
- Recognizes human pyrin.
- Réactivité croisée
- Humain
- Immunogène
- Synthetic peptide corresponding to aa 2-29 (A2KTPSDHLLSTLEELVPYDFEKFKFKLQ29) of human pyrin.
- Top Product
- Discover our top product MEFV Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- In PBS containing 10 % glycerol and 0.02 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
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Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 1 year after receipt when stored at -20°C. - Date de péremption
- 12 months
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The SPRY domain of Pyrin, mutated in familial Mediterranean fever patients, interacts with inflammasome components and inhibits proIL-1beta processing." dans: Cell death and differentiation, Vol. 14, Issue 8, pp. 1457-66, (2007) (PubMed).
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The SPRY domain of Pyrin, mutated in familial Mediterranean fever patients, interacts with inflammasome components and inhibits proIL-1beta processing." dans: Cell death and differentiation, Vol. 14, Issue 8, pp. 1457-66, (2007) (PubMed).
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- Antigène
- MEFV (Mediterranean Fever (MEFV))
- Autre désignation
- Pyrin (MEFV Produits)
- Synonymes
- anticorps pyrin, anticorps MEFV, anticorps FMF, anticorps MEF, anticorps TRIM20, anticorps rfp domain, anticorps MEFV, pyrin innate immunity regulator, anticorps Mediterranean fever, anticorps MEFV, anticorps Mefv
- Sujet
- Pyrin regulates inflammation by interacting with the cytoskeleton. Pyrin may direct the migration of white blood cells to sites of inflammation and stop or slow the inflammatory response when it is no longer needed. Defects in pyrin are the cause for Mediterranean fever.
- UniProt
- O15553
- Pathways
- Positive Regulation of Endopeptidase Activity
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