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ITGA5 anticorps

ITGA5 Reactivité: Souris FACS, IHC (fro), IF, BR, IHC (f) Hôte: Rat Monoclonal 5H10-27 unconjugated
N° du produit ABIN1176992
  • Antigène Voir toutes ITGA5 Anticorps
    ITGA5 (Integrin, alpha 5 (ITGA5))
    Reactivité
    • 107
    • 67
    • 19
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Souris
    Hôte
    • 86
    • 22
    • 13
    • 2
    • 1
    Rat
    Clonalité
    • 76
    • 49
    Monoclonal
    Conjugué
    • 62
    • 12
    • 11
    • 9
    • 7
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp ITGA5 est non-conjugé
    Application
    • 84
    • 50
    • 48
    • 39
    • 16
    • 15
    • 14
    • 13
    • 11
    • 10
    • 10
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF), Blocking Reagent (BR), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
    Marque
    BD Pharmingen™
    Purification
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    Stérilité
    0.2 μm filtered
    niveau d'endotoxine
    Endotoxin level is ≤ 0.01 EU/μg (≤ 0.001 ng/μg) of protein as determined by the LAL assay.
    Immunogène
    Mouse mast cell line MC/9
    Clone
    5H10-27
    Isotype
    IgG2a kappa
    Top Product
    Discover our top product ITGA5 Anticorps primaire
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1.0 mg/mL
    Buffer
    No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered.
    Agent conservateur
    Azide free
    Stock
    4 °C
    Stockage commentaire
    Store undiluted at 4°C. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
  • Cukierman, Pankov, Stevens, Yamada: "Taking cell-matrix adhesions to the third dimension." dans: Science (New York, N.Y.), Vol. 294, Issue 5547, pp. 1708-12, (2001) (PubMed).

    Yang, Hynes: "Fibronectin receptor functions in embryonic cells deficient in alpha 5 beta 1 integrin can be replaced by alpha V integrins." dans: Molecular biology of the cell, Vol. 7, Issue 11, pp. 1737-48, (1997) (PubMed).

    Ruppert, Aigner, Hubbe, Yagita, Altevogt: "The L1 adhesion molecule is a cellular ligand for VLA-5." dans: The Journal of cell biology, Vol. 131, Issue 6 Pt 2, pp. 1881-91, (1996) (PubMed).

    Rich, Van Nood, Lee: "Role of alpha 5 beta 1 integrin in TGF-beta 1-costimulated CD8+ T cell growth and apoptosis." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 157, Issue 7, pp. 2916-23, (1996) (PubMed).

    Gomez, Cano: "Expression of beta 1 integrin receptors in transformed mouse epidermal keratinocytes: upregulation of alpha 5 beta 1 in spindle carcinoma cells." dans: Molecular carcinogenesis, Vol. 12, Issue 3, pp. 153-65, (1995) (PubMed).

    Hardy, Minguell: "Modulation of the adhesion of hemopoietic progenitor cells to the RGD site of fibronectin by interleukin 3." dans: Journal of cellular physiology, Vol. 164, Issue 2, pp. 315-23, (1995) (PubMed).

    Halvorson, Coligan: "Enhancement of VLA integrin receptor function on thymocytes by cAMP is dependent on the maturation stage of the thymocytes." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 155, Issue 10, pp. 4567-74, (1995) (PubMed).

    Kinashi, Springer: "Adhesion molecules in hematopoietic cells." dans: Blood cells, Vol. 20, Issue 1, pp. 25-44, (1995) (PubMed).

  • Antigène
    ITGA5 (Integrin, alpha 5 (ITGA5))
    Autre désignation
    CD49e (ITGA5 Produits)
    Synonymes
    anticorps ITGA5, anticorps Cd49e, anticorps Fnra, anticorps VLA5, anticorps CD49e, anticorps FNRA, anticorps VLA5A, anticorps Itga5_retired, anticorps integrin subunit alpha 5, anticorps integrin alpha 5 (fibronectin receptor alpha), anticorps ITGA5, anticorps Itga5
    Sujet
    The 5H10-27 (MFR5) antibody reacts with the alpha5 chain of the integrin alpha5beta1 fibronectin receptor (CD49e/CD29, VLA-5) on thymocytes, activated T lymphocytes, mast cells, and a variety of mouse cell lines, but not splenocytes. Soluble 5H10-27 (MFR5) antibody has been reported to inhibit VLA-5-mediated functions in vitro. In addition, immobilized mAb 5H10-27 (MFR5) has been demonstrated to costimulate the proliferative response of CD8+ T cells to plate-bound anti-CD3e antibody.
    Synonyms: Integrin alpha5 chain
    Pathways
    Integrin Complex
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