Aromatase anticorps

N° du produit ABIN126953

Détail du produit anti-Aromatase anticorps

Antigène: Aromatase (CYP19A1) (Cytochrome P450, Family 19, Subfamily A, Polypeptide 1 (CYP19A1))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Aromatase est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: This antibody recognizes Aromatase p450AROM.

Réactivité croisée (Details): Species reactivity (expected):Mouse, Rat, Rabbit, Bovine, Sheep, Porcine, Equine (Horse) and Chicken.
Species reactivity (tested):Human.

Purification: Immunoaffinity Chromatography

Immunogène: Synthetic peptide surronding amino acid 385 of Human Aromatase Genename: CYP19A1

Information d'application

Indications d'application: Immunohistochemistry (10-20 μg/mL). Western blotting (0.5-4 μg/mL): A 55 kDa band can be detected, corresponding to theexpected molecular weight of Aromatase, an additional 35 kDa band (believed to be thecleavage product of Aromatase) can also be detected in Jurkat cells.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.2 mg/mL

Buffer: PBS containing 30 % Glycerol, 0.5 % BSA, 5 mM EDTA and 0.01 % Thimerosal as preservative

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store the antibody at -20 °C or aliquot and freeze at -70 °C for long term storage. Should this product contain a precipitate we recommend microcentrifugation before use.

Détails sur Aromatase

Antigène: Aromatase (CYP19A1) (Cytochrome P450, Family 19, Subfamily A, Polypeptide 1 (CYP19A1))

Autre désignation: Aromatase (CYP19A1 Produits)

Synonymes: anticorps ARO, anticorps ARO1, anticorps CPV1, anticorps CYAR, anticorps CYP19, anticorps CYPXIX, anticorps P-450AROM, anticorps Aromatase, anticorps Cyp19, anticorps Cyp19a, anticorps p450arom, anticorps P450 arom, anticorps aro, anticorps cyp19, anticorps cyp19a, anticorps p450arom-A, anticorps P450AROM, anticorps Ar, anticorps ArKO, anticorps Int-5, anticorps Int5, anticorps CYP19P1, anticorps CYP19A1, anticorps CYP19a1, anticorps P450aromA, anticorps ar1, anticorps cypXIX, anticorps etID309862.18, anticorps zgc:136541, anticorps AroB, anticorps CYP19a2, anticorps P450aromB, anticorps cyp19b, anticorps zgc:92614, anticorps cyp19a1, anticorps cytochrome P450 family 19 subfamily A member 1, anticorps cytochrome P450, family 19, subfamily a, polypeptide 1, anticorps cytochrome P450 family 19 subfamily A member 1 L homeolog, anticorps aromatase, anticorps cytochrome P450 aromatase, anticorps cytochrome P450, family 19, subfamily A, polypeptide 1, anticorps cytochrome P450 19A1, anticorps cytochrome P450, family 17, subfamily A, polypeptide 1, anticorps cytochrome P450, family 19, anticorps cytochrome P450, family 19, subfamily A, polypeptide 1a, anticorps cytochrome P450, family 19, subfamily A, polypeptide 1b, anticorps cytochrome P450 19A1-like, anticorps CYP19A1, anticorps Cyp19a1, anticorps cyp19a1.L, anticorps SAV_2383, anticorps pfcyp19b-tstr, anticorps CYP19, anticorps cyp19a1a, anticorps cyp19a1b, anticorps LOC101174651

Sujet: Aromatase is a key enzyme in steroidogenesis and plays an important role in sexual differentiation, oestrogen biosynthesis, fertility and carcinogenesis. It is highly conserved amongst mammals, and is highly expressed in placental tissue. Many environmental chemicals may influence aromatase activity and thereby disrupt endocrine function.Synonyms: ARO1, CYAR, CYP19, CYP19A1, CYPXIX, Cytochrome P450 19A1, Estrogen synthetase, P450AROM

ID gène: 1588, 9606

UniProt: P11511

Pathways: Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis, C21-Steroid Hormone Metabolic Process, Carbohydrate Homeostasis