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IL3RA anticorps

IL3RA Reactivité: Humain WB, FACS, IP, IHC (fro) Hôte: Souris Monoclonal 6H6 unconjugated
N° du produit ABIN1302506
  • Antigène Voir toutes IL3RA Anticorps
    IL3RA (Interleukin 3 Receptor, alpha (IL3RA))
    Reactivité
    • 90
    • 29
    • 3
    Humain
    Hôte
    • 48
    • 45
    • 6
    • 1
    Souris
    Clonalité
    • 54
    • 45
    • 1
    Monoclonal
    Conjugué
    • 48
    • 11
    • 7
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp IL3RA est non-conjugé
    Application
    • 60
    • 60
    • 19
    • 15
    • 13
    • 13
    • 11
    • 9
    • 7
    • 5
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Specificité
    The mouse monoclonal antibody 6H6 recognizes an extracellular epitope of CD123 (interleukin 3 receptor alpha), a 60-70 kDa transmembrane protein expressed by myeloid precursors, megakaryocytes, macrophages, dendritic cells, mast cells, basophils, and some B cells. This antibody does not inhibit IL-3 binding to its receptor.
    Réactivité croisée (Details)
    Human
    Purification
    Purified by protein-A affinity chromatography.
    Pureté
    > 95 % (by SDS-PAGE)
    Immunogène
    IL3 receptor alpha chain expressed on the surface of transiently transfected COS cells
    Clone
    6H6
    Isotype
    IgG1
    Top Product
    Discover our top product IL3RA Anticorps primaire
  • Indications d'application
    Flow cytometry: Recommended dilution: 1-4 μg/mL.
    Restrictions
    For Research Use only
  • Concentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Do not freeze.
    Stock
    4 °C
    Stockage commentaire
    Store at 2-8°C. Do not freeze.
  • Martín-Gayo, Sierra-Filardi, Corbí, Toribio: "Plasmacytoid dendritic cells resident in human thymus drive natural Treg cell development." dans: Blood, Vol. 115, Issue 26, pp. 5366-75, (2010) (PubMed).

    Herling, Teitell, Shen, Medeiros, Jones: "TCL1 expression in plasmacytoid dendritic cells (DC2s) and the related CD4+ CD56+ blastic tumors of skin." dans: Blood, Vol. 101, Issue 12, pp. 5007-9, (2003) (PubMed).

  • Antigène
    IL3RA (Interleukin 3 Receptor, alpha (IL3RA))
    Autre désignation
    CD123 (IL3RA Produits)
    Synonymes
    anticorps CD123, anticorps IL3R, anticorps IL3RAY, anticorps IL3RX, anticorps IL3RY, anticorps hIL-3Ra, anticorps CDw123, anticorps SUT-1, anticorps Cyrl, anticorps interleukin 3 receptor subunit alpha, anticorps interleukin 3 receptor, alpha chain, anticorps IL3RA, anticorps Il3ra
    Sujet
    Interleukin 3 receptor subunit alpha,CD123 is the alpha chain of interleukin 3 receptor (IL-3R alpha). This subunit heterodimerizes with the interleukin 3 receptor beta chain (CD131), which is shared with other receptors. CD123 interacts with IL-3 specifically, but with low affinity, and association with the beta subunit confers high affinity binding to the receptor heterodimer. Both chains are required for signaling, but receptor activation and signal transduction depend on IL-3 binding to CD123 as the initial step.,IL3RA, MGC34174, hIL-3Ra
    ID gène
    3563
    UniProt
    P26951
    Pathways
    Signalistation JAK/STAT
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