RT1-BB anticorps (Biotin)

N° du produit ABIN133237

Détail du produit anti-RT1-BB anticorps (Biotin)

Antigène: RT1-BB (RT1 Class II, Locus Bb (RT1-BB))

Reactivité: Rat, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp RT1-BB est conjugé à/à la Biotin

Application: Flow Cytometry (FACS)

Specificité: Rat RT1.B (Rat Ia-non-polymorphic)

Immunogène: Rat thymocyte membrane glycoprotein . Fusion Partner: PS-NS1-1-Ag4 (NS1/1) . Donor: BALB/c spleen

Clone: OX-6

Isotype: IgG1

Information d'application

Indications d'application: This clone is reported to work with frozen and paraffin sections (5).

Restrictions: For Research Use only

Stockage

Concentration: 0.1 mg/ml

Buffer: Biotin conjugated Ig buffered in PBS, 0.02% NaN and EIA grade BSA as a stabilizing protein concentration to 4-5 mg/ml.. (Purified from ascitic fluid via Protein G Chromatography)

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Détails sur RT1-BB

Antigène: RT1-BB (RT1 Class II, Locus Bb (RT1-BB))

Autre désignation: RT1.B (RT1-BB Produits)

Synonymes: anticorps RT1.B, anticorps RT1 class II, locus Bb, anticorps RT1-Bb

Sujet: Biotin anti-rat RT1.B monoclonal antibody recognizes Ia from all rat strains tested. It labels a monomorphic determinant of the rat Ia antigen present on the majority of peripheral B lymphocytes, dendritic cells, some macrophages, and certain epithelial cells (2,3,4) but not peripheral T lymphocytes. (4) This antibody also cross reacts with murine Ia antigens (particularly with k and s haplotypes). Analysis of recombinant strains shows that the determinant maps to the I-A region of the mouse MHC (1,2) and correlates with mouse Ia specificity 17 or 18. Thus, the determinant recognized by ABIN133237is polymorphic in the mouse. This antibody may be useful for recognizing the rat Ia antigen and can be coupled to Sepharose 4B for purification of rat Ia antigen by antibody affinity chromatography (1). This clone is reported to work with frozen and paraffin sections (5).

Pathways: Production of Molecular Mediator of Immune Response