RT1-BB anticorps (FITC)

N° du produit ABIN133238

Détail du produit anti-RT1-BB anticorps (FITC)

Antigène: RT1-BB (RT1 Class II, Locus Bb (RT1-BB))

Reactivité: Rat, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp RT1-BB est conjugé à/à la FITC

Application: Flow Cytometry (FACS)

Specificité: Rat RT1.B (Rat Ia-non-polymorphic)

Purification: Purified from ascites via Protein G Chromatography

Immunogène: rat thymocyte membrane glycoprotein . Fusion Partner: P3-NS1-1-AG4 (NS1/1) . Donor: BALB/c spleen

Clone: OX-6

Isotype: IgG1

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Concentration: 0.1 mg/ml

Buffer: FITC conjugated Ig buffered in PBS, 0.02% NaN3 and EIA grade BSA as a stabilizing protein to bring total protein concentration to 4-5 mg/ml.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Détails sur RT1-BB

Antigène: RT1-BB (RT1 Class II, Locus Bb (RT1-BB))

Autre désignation: RT1.B (RT1-BB Produits)

Synonymes: anticorps RT1.B, anticorps RT1 class II, locus Bb, anticorps RT1-Bb

Sujet: Anti-rat RT1.B monoclonal antibody recognizes Ia from all rat strains tested. It labels a monomorphic determinant of the rat Ia antigen present on the majority of peripheral B lymphocytes, dendritic cells, some macrophages, and certain epithelial cells (2,3,4) but not peripheral T lymphocytes. (4) This antibody also cross reacts with murine Ia antigens (particularly with k and s haplotypes). Analysis of recombinant strains shows that the determinant maps to the I-A region of the mouse MHC (1,2) and correlates with mouse Ia specificity 17 or 18. Thus, the determinant recognized by ABIN133238is polymorphic in the mouse. This antibody may be useful for recognizing the rat Ia antigen and can be coupled to Sepharose 4B for purification of rat Ia antigen by antibody affinity chromatography (1).

Pathways: Production of Molecular Mediator of Immune Response