LAMP2 anticorps

N° du produit ABIN133965

Détail du produit anti-LAMP2 anticorps

Antigène: LAMP2 (Lysosomal-Associated Membrane Protein 2 (LAMP2))

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp LAMP2 est non-conjugé

Application: Flow Cytometry (FACS)

Specificité: Mouse MAC-3

Purification: Purified

Immunogène: Immunoadsorbent purified mouse macrophage glycoprotein fraction. . Fusion Partner: NS-1 . Donor: Rat spleen

Isotype: IgG1

Information d'application

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/ml

Stock: 4 °C

Références pour anticorps anti-LAMP2 (ABIN133965)

Lindsey, Ma, Flynn, Winniford, Hall, DeLeon-Pennell: "Identifying the molecular and cellular signature of cardiac dilation following myocardial infarction." dans: Biochimica et biophysica acta. Molecular basis of disease, Vol. 1865, Issue 7, pp. 1845-1852, (2020) (PubMed).

Jung, Ma, Iyer, DeLeon-Pennell, Yabluchanskiy, Garrett, Lindsey: "IL-10 improves cardiac remodeling after myocardial infarction by stimulating M2 macrophage polarization and fibroblast activation." dans: Basic research in cardiology, Vol. 112, Issue 3, pp. 33, (2018) (PubMed).

Kain, Ingle, Colas, Dalli, Prabhu, Serhan, Joshi, Halade: "Resolvin D1 activates the inflammation resolving response at splenic and ventricular site following myocardial infarction leading to improved ventricular function." dans: Journal of molecular and cellular cardiology, Vol. 84, pp. 24-35, (2016) (PubMed).

Iyer, Patterson, Zouein, Ma, Dive, de Castro Brás, Lindsey: "Early matrix metalloproteinase-12 inhibition worsens post-myocardial infarction cardiac dysfunction by delaying inflammation resolution." dans: International journal of cardiology, Vol. 185, pp. 198-208, (2016) (PubMed).

Yan, Zhou, Hu, Pham: "Suppression of experimental arthritis through AMP-activated protein kinase activation and autophagy modulation." dans: Journal of rheumatic diseases and treatment, Vol. 1, Issue 1, pp. 5, (2015) (PubMed).

DeLeon-Pennell, de Castro Brás, Iyer, Bratton, Jin, Ripplinger, Lindsey: "P. gingivalis lipopolysaccharide intensifies inflammation post-myocardial infarction through matrix metalloproteinase-9." dans: Journal of molecular and cellular cardiology, Vol. 76, pp. 218-26, (2015) (PubMed).

Zhou, Yan, Hu, Springer, Yang, Wickline, Pan, Lanza, Pham: "Fumagillin prodrug nanotherapy suppresses macrophage inflammatory response via endothelial nitric oxide." dans: ACS nano, Vol. 8, Issue 7, pp. 7305-17, (2015) (PubMed).

Deleon-Pennell, de Castro Brás, Lindsey: "Circulating Porphyromonas gingivalis lipopolysaccharide resets cardiac homeostasis in mice through a matrix metalloproteinase-9-dependent mechanism." dans: Physiological reports, Vol. 1, Issue 5, pp. e00079, (2014) (PubMed).

Heaberlin, Ma, Zhang, Ahuja, Lindsey, Halade: "Obese and diabetic KKAy mice show increased mortality but improved cardiac function following myocardial infarction." dans: Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology, Vol. 22, Issue 6, pp. 481-7, (2014) (PubMed).

Zamilpa, Ibarra, de Castro Brás, Ramirez, Nguyen, Halade, Zhang, Dai, Dayah, Chiao, Lowell, Ahuja, DArmiento, Jin, Lindsey: "Transgenic overexpression of matrix metalloproteinase-9 in macrophages attenuates the inflammatory response and improves left ventricular function post-myocardial infarction." dans: Journal of molecular and cellular cardiology, Vol. 53, Issue 5, pp. 599-608, (2013) (PubMed).

Ma, Chiao, Zhang, Manicone, Jin, Lindsey: "Matrix metalloproteinase-28 deletion amplifies inflammatory and extracellular matrix responses to cardiac aging." dans: Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada, Vol. 18, Issue 1, pp. 81-90, (2012) (PubMed).

Chiao, Dai, Zhang, Lin, Lopez, Ahuja, Chou, Lindsey, Jin: "Multi-analyte profiling reveals matrix metalloproteinase-9 and monocyte chemotactic protein-1 as plasma biomarkers of cardiac aging." dans: Circulation. Cardiovascular genetics, Vol. 4, Issue 4, pp. 455-62, (2012) (PubMed).

Détails sur LAMP2

Antigène: LAMP2 (Lysosomal-Associated Membrane Protein 2 (LAMP2))

Autre désignation: MAC-3 (LAMP2 Produits)

Synonymes: anticorps CD107b, anticorps LAMP-2, anticorps LAMPB, anticorps LGP110, anticorps Lamp-2, anticorps Lamp-2a, anticorps Lamp-2b, anticorps Lamp-2c, anticorps Mac3, anticorps cd107b, anticorps lamp-2, anticorps lampb, anticorps LAMP2, anticorps lamp2, anticorps DKFZp459J126, anticorps LGP-B, anticorps sb:cb587, anticorps wu:fb14a06, anticorps zgc:103532, anticorps lysosomal associated membrane protein 2, anticorps lysosomal-associated membrane protein 2, anticorps lysosomal-associated membrane protein 2 S homeolog, anticorps lysosomal membrane glycoprotein 2, anticorps LAMP2, anticorps Lamp2, anticorps lamp2.S, anticorps lamp2

Sujet: Anti-mouse MAC-3 monoclonal antibody recognizes the MAC-3 antigen which is found on macrophages and some nonlymphoid tissues, but not on lymphocytes. It is a glycoprotein showing a broad band in SDS-PAGE, and is synthesized by macrophages (molecular weight 92-110,000 daltons, depending on the origin of macrophages). It reacts with peritoneal exudate macrophages where the exudate is provoked by thioglycollate, protease peptone, L. monocytogenes, lipopolysaccharide and concanavalin A. It does not react with thymocytes, spleen, lymph node or bone marrow cells in immunofluorescent flow cytometry. MAC-3 is a general marker for macrophages and can be used to distinguish these cells from lymphocytes. MAC-3 is differentiated from MAC-1 and MAC-2 antigens by its M (average)110,000 and by cell distribution.

Pathways: Autophagy