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CD40 anticorps

CD40 Reactivité: Souris FACS Hôte: Rat Monoclonal 1C10 unconjugated
N° du produit ABIN135211
  • Antigène Voir toutes CD40 Anticorps
    CD40
    Reactivité
    • 198
    • 113
    • 22
    • 20
    • 7
    • 6
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Souris
    Hôte
    • 113
    • 100
    • 54
    • 6
    • 2
    • 1
    • 1
    • 1
    Rat
    Clonalité
    • 182
    • 89
    • 5
    Monoclonal
    Conjugué
    • 124
    • 26
    • 22
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    • 14
    • 8
    • 7
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CD40 est non-conjugé
    Application
    • 157
    • 97
    • 64
    • 54
    • 32
    • 32
    • 20
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    • 17
    • 14
    • 13
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    Flow Cytometry (FACS)
    Specificité
    Mouse CD40, Mr 45-50 kDa
    Attributs du produit
    Rat Anti-Mouse CD40-UNLB
    Purification
    Purified
    Immunogène
    sCD40
    Clone
    1C10
    Isotype
    IgG2a
    Top Product
    Discover our top product CD40 Anticorps primaire
  • Indications d'application
    • Applications: FC - Quality tested , IP - Reported in literature , Activ - Reported in literature , Block - Reported in literature
    • Working Dilutions: Flow Cytometry FITC and BIOT conjugates 2 g/106 cells PE, APC, and SPRD conjugates 0.5 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L
    Commentaires

    In vitro induction of proliferation of mature B lymphocyte

    Volume d'échantillon
    1 mL
    Restrictions
    For Research Use only
  • Concentration
    0.5 mg/mL
    Buffer
    0.5 mg of purified immunoglobulin in 1.0 mL of borate buffered saline,  pH 8.2. No preservatives or amine-containing buffer salts added
    Agent conservateur
    Without preservative
    Conseil sur la manipulation
    Each reagent is stable for the period shown on the bottle label if stored as directed.
    Stock
    4 °C
    Stockage commentaire
    Store at 2-8°C
  • Duarte, Cragnolini, Swee, Bilate, Bader, Ingram, Rashidfarrokhi, Fang, Schiepers, Hanke, Ploegh: "Generation of Immunity against Pathogens via Single-Domain Antibody-Antigen Constructs." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 197, Issue 12, pp. 4838-4847, (2017) (PubMed).

  • Antigène
    CD40
    Autre désignation
    CD40 (CD40 Produits)
    Synonymes
    anticorps Bp50, anticorps CDW40, anticorps TNFRSF5, anticorps p50, anticorps AI326936, anticorps GP39, anticorps HIGM1, anticorps IGM, anticorps IMD3, anticorps T-BAM, anticorps TRAP, anticorps Tnfrsf5, anticorps TNFSF5, anticorps CD40 molecule, anticorps CD40 antigen, anticorps CD40, anticorps Cd40
    Sujet
    CD40 is a type I cell surface protein belonging to the tumor necrosis factor superfamily of cell surface receptors. In mice it is expressed on B lineage cells, follicular dendritic cells, thymic epithelium, and interdigitating cells in the T-cell zone of secondary lymphoid organs. CD40 first becomes detectable on a subset of small pre-B II cells in bone marrow, with the levels of CD40 expression increasing thereafter during B-cell maturation. Immature B cells (IgM+IgDloB220lo) express intermediate levels of CD40, whereas mature B cells (IgM+IgDhiB220hi) express high levels. CD40 has a central role in B cell growth and differentiation, and signalling through CD40 in combination with IL-4 reportedly induces immunoglobulin isotype switching and secretion of IgE.
    Pathways
    Signalisation NF-kappaB, Cellular Response to Molecule of Bacterial Origin, M Phase, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
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