TXNRD1 anticorps (AA 451-550)

N° du produit ABIN1386102

Détail du produit anti-TXNRD1 anticorps

Antigène: TXNRD1 (Thioredoxin Reductase 1 (TXNRD1))

Épitope: AA 451-550

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TXNRD1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Humain, Souris, Rat

Homologie: Dog,Cow,Pig,Horse

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human TXNRD1

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-TXNRD1 (ABIN1386102)

Kaya, Çiçek, Erdi, Findik, Karatas, Esen, Keskin, Kalkan: "Intratumoral hemorrhage-related differences in the expression of vascular endothelial growth factor, basic fibroblast growth factor and thioredoxin reductase 1 in human glioblastoma." dans: Molecular and clinical oncology, Vol. 5, Issue 4, pp. 343-346, (2016) (PubMed).

Détails sur TXNRD1

Antigène: TXNRD1 (Thioredoxin Reductase 1 (TXNRD1))

Autre désignation: Txnrd1 (TXNRD1 Produits)

Synonymes: anticorps TrxR1, anticorps cb682, anticorps fb83a08, anticorps wu:fb83a08, anticorps GB14972, anticorps MGC85342, anticorps NADPH-dependent thioredoxin reductase C, anticorps T32G6.20, anticorps T32G6_20, anticorps GRIM-12, anticorps TR, anticorps TR1, anticorps TRXR1, anticorps TXNR, anticorps Tr, anticorps thioredoxin reductase 1, anticorps thioredoxin reductase 1 L homeolog, anticorps NADPH-dependent thioredoxin reductase C, anticorps ThioRedoXin Reductase, anticorps TXNRD1, anticorps txnrd1, anticorps Trxr-1, anticorps txnrd1.L, anticorps NTRC, anticorps trxr-1, anticorps Txnrd1

Sujet:

Synonyms: TR, TR1, TXNR, TRXR1, GRIM-12, Thioredoxin reductase 1, cytoplasmic, Gene associated with retinoic and interferon-induced mortality 12 protein, Gene associated with retinoic and IFN-induced mortality 12 protein, KM-12-derived reductase-like factor, Thioredoxin reductase TR1, TXNRD1, GRIM12, KDRF

Background: Isoform 1 may possess glutaredoxin activity as well as thioredoxin reductase activity and induces actin and tubulin polymerization, leading to formation of cell membrane protrusions. Isoform 4 enhances the transcriptional activity of estrogen receptors alpha and beta while isoform 5 enhances the transcriptional activity of the beta receptor only. Isoform 5 also mediates cell death induced by a combination of interferon-beta and retinoic acid.

ID gène: 7296

UniProt: Q16881

Pathways: Regulation of Lipid Metabolism by PPARalpha, Regulation of Carbohydrate Metabolic Process, Cell RedoxHomeostasis