TXNRD1 anticorps (Thioredoxin Reductase 1) (AA 440-490)

Details for Product anti-TXNRD1 Antibody No. ABIN1386102, Fournisseur: Connectez-vous pour afficher
Antigène
  • TrxR1
  • cb682
  • fb83a08
  • wu:fb83a08
  • GB14972
  • MGC85342
  • NADPH-dependent thioredoxin reductase C
  • T32G6.20
  • T32G6_20
  • GRIM-12
  • TR
  • TR1
  • TRXR1
  • TXNR
  • Tr
  • thioredoxin reductase 1
  • thioredoxin reductase 1 L homeolog
  • NADPH-dependent thioredoxin reductase C
  • ThioRedoXin Reductase
  • TXNRD1
  • txnrd1
  • Trxr-1
  • txnrd1.L
  • NTRC
  • trxr-1
  • Txnrd1
Épitope
AA 440-490
17
14
11
6
5
5
3
3
2
2
2
1
1
Reactivité
Humain, Souris, Rat (Rattus)
125
44
35
5
1
1
Hôte
Lapin
72
42
21
Clonalité
Polyclonal
Conjugué
Cet anticorp TXNRD1 est non-conjugé
7
5
3
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
95
59
32
32
19
14
12
12
11
10
3
2
1
1
Options
Fournisseur
Connectez-vous pour afficher
N° du produit (Fournisseur)
Connectez-vous pour afficher
Immunogène KLH conjugated synthetic peptide derived from human TXNRD1
Isotype IgG
Purification Purified by Protein A.
Plasmids, Primers & others Plasmids, Primers & others TXNRD1 products on genomics-online (e.g. as negative or positive controls)
Antigène
Autre désignation Txnrd1 (TXNRD1 Antibody Extrait)
Sujet

Isoform 1 may possess glutaredoxin activity as well as thioredoxin reductase activity and induces actin and tubulin polymerization, leading to formation of cell membrane protrusions. Isoform 4 enhances the transcriptional activity of estrogen receptors alpha and beta while isoform 5 enhances the transcriptional activity of the beta receptor only. Isoform 5 also mediates cell death induced by a combination of interferon-beta and retinoic acid.

Subcellular location: Cytoplasm

Synonyms: TR, TR1, TXNR, TRXR1, GRIM-12, Thioredoxin reductase 1, cytoplasmic, Gene associated with retinoic and interferon-induced mortality 12 protein, Gene associated with retinoic and IFN-induced mortality 12 protein, KM-12-derived reductase-like factor, Thioredoxin reductase TR1, TXNRD1, GRIM12, KDRF

ID gène 7296
UniProt Q16881
Pathways Regulation of Lipid Metabolism by PPARalpha, Regulation of Carbohydrate Metabolic Process, Cell RedoxHomeostasis
Indications d'application WB 1:100-1000
IHC-P 1:100-500
IF(IHC-P) 1:50-200
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Agent conservateur Sodium azide
Précaution d'utilisation This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Stock -20 °C
Stockage commentaire Store at -20°C
Date de péremption 12 months
Images (Fournisseur)
Immunohistochemistry (IHC) image for anti-Thioredoxin Reductase 1 (TXNRD1) (AA 440-490) antibody (ABIN1386102) Formalin-fixed and paraffin embedded human kidney labeled with Anti-TXNRD1 Polyclonal...
Immunohistochemistry (IHC) image for anti-Thioredoxin Reductase 1 (TXNRD1) (AA 440-490) antibody (ABIN1386102) Formalin-fixed and paraffin embedded mouse spleen labeled with Anti-TXNRD1 Polyclonal...
Immunohistochemistry (IHC) image for anti-Thioredoxin Reductase 1 (TXNRD1) (AA 440-490) antibody (ABIN1386102) Formalin-fixed and paraffin embedded rat testis labeled with Anti-TXNRD1 Polyclonal A...
SDS-PAGE (SDS) image for anti-Thioredoxin Reductase 1 (TXNRD1) (AA 440-490) antibody (ABIN1386102) Lane 1: rat brain lysates Lane 2: rat heart lysates probed with Anti TXNRD1 Polyclona...
Produit citée dans: Kaya, Çiçek, Erdi, Findik, Karatas, Esen, Keskin, Kalkan: "Intratumoral hemorrhage-related differences in the expression of vascular endothelial growth factor, basic fibroblast growth factor and thioredoxin reductase 1 in human glioblastoma." dans: Molecular and clinical oncology, Vol. 5, Issue 4, pp. 343-346, 2016 (PubMed). Méthode utilisée: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (Échantillon (espèces): Human). Détails: Sample: tumor

Avez-vous cherché autre chose?