PPP1R10 anticorps (AA 151-250)

N° du produit ABIN1386277

Détail du produit anti-PPP1R10 anticorps

Antigène: PPP1R10 (Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 10 (PPP1R10))

Épitope: AA 151-250

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PPP1R10 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Humain, Souris, Rat

Homologie: Dog,Cow,Sheep,Pig

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human PNUTS/PPP1R10

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur PPP1R10

Antigène: PPP1R10 (Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 10 (PPP1R10))

Autre désignation: PNUTS/PPP1R10 (PPP1R10 Produits)

Synonymes: anticorps CAT53, anticorps FB19, anticorps PNUTS, anticorps PP1R10, anticorps R111, anticorps p99, anticorps Fb19, anticorps Pnuts, anticorps 2610025H06Rik, anticorps Cat53, anticorps D17Ertd808e, anticorps CHUNP6885, anticorps fe15d12, anticorps fk54b08, anticorps ppp1r10l, anticorps wu:fe15d12, anticorps wu:fk54b08, anticorps protein phosphatase 1 regulatory subunit 10, anticorps protein phosphatase 1, regulatory subunit 10, anticorps protein phosphatase 1 regulatory subunit 10 S homeolog, anticorps PPP1R10, anticorps Ppp1r10, anticorps ppp1r10.S, anticorps ppp1r10

Sujet:

Synonyms: CAT 53, CAT53, FB 19, FB19, FB19 protein, MHC class I region proline rich protein CAT53, p99, Phosphatase 1 nuclear targeting subunit, Phosphatase nuclear targeting subunit, PNUTS, PP1 binding protein of 114 kDa, PP1R10, Protein phosphatase 1 regulatory inhibitor subunit 10, Protein phosphatase 1 regulatory subunit 10, Serine/threonine protein phosphatase 1 regulatory subunit 10, PP1RA_HUMAN.

Background: Eukaryotic protein phosphorylation and dephosphorylation on serine and threonine residues regulates numerous cell functions, including division, homeostasis and apoptosis. A group of proteins that play a major role in this process are the serine/threonine protein phosphatases. Protein phosphatase (PP) holoenzyme is a trimeric complex that contains a regulatory subunit, a variable subunit and a catalytic subunit. Families of PP catalytic subunits include PP1, PP2A, PP2B, PP2C, PPX and PP5. Regulatory subunits include nuclear inhibitor of PP1 (NIPP1), PP1 nuclear targeting subunit (PNUTS), PP2A-A, PP2A-B, PP2A-B56, PP2A-C, PP2B-B and PR48. PNUTS, also designated CAT53 or FB19, is encoded by the gene PPP1R10. PNUTS acts as an inhibitor for the phosphatase activity of PP1 Alpha and PP1 Gamma. It is a nuclear protein primarily detected in nucleoplasmic bodies and within nucleoli. PNUTS expression levels are highest in brain, heart, lung, placenta, liver, kidney, pancreas and skeletal muscle.

Pathways: Protein targeting to Nucleus