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BBS10 anticorps (AA 51-130)

BBS10 Reactivité: Humain WB, ELISA, IF (cc), IF (p), IHC (p), ICC, IHC (fro) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN1386551
  • Antigène Voir toutes BBS10 Anticorps
    BBS10 (Bardet-Biedl Syndrome 10 (BBS10))
    Épitope
    • 14
    • 8
    • 8
    • 6
    • 4
    • 2
    • 1
    • 1
    AA 51-130
    Reactivité
    • 39
    • 2
    • 1
    • 1
    Humain
    Hôte
    • 38
    • 1
    Lapin
    Clonalité
    • 39
    Polyclonal
    Conjugué
    • 12
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp BBS10 est non-conjugé
    Application
    • 35
    • 19
    • 13
    • 12
    • 12
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Homologie
    Human,Mouse,Rat
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human BBS10
    Isotype
    IgG
    Top Product
    Discover our top product BBS10 Anticorps primaire
  • Indications d'application
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Date de péremption
    12 months
  • Antigène
    BBS10 (Bardet-Biedl Syndrome 10 (BBS10))
    Autre désignation
    BBS10 (BBS10 Produits)
    Synonymes
    anticorps MGC84945, anticorps si:dkey-30c15.16, anticorps C12orf58, anticorps RGD1560748, anticorps 1300007O09Rik, anticorps AI452285, anticorps Bardet-Biedl syndrome 10, anticorps Bardet-Biedl syndrome 10 L homeolog, anticorps Bardet-Biedl syndrome 10 (human), anticorps BBS10, anticorps bbs10.L, anticorps bbs10, anticorps Bbs10
    Sujet

    Synonyms: Bardet Biedl syndrome 10 protein, Bardet Biedl syndrome 10 protein homolog, C12orf58, FLJ23560, RGD1560748, BBS10_HUMAN.

    Background: Bardet-Biedl syndrome (BBS) is a pleiotropic genetic disorder characterized by obesity, photoreceptor degeneration, polydactyly, hypogenitalism, renal abnormalities, and developmental delay. Other associated clinical findings in BBS patients include diabetes, hypertension, and congenital heart defects. BBS genes map to multiple loci and encode fourteen proteins, BBS1-BBS14. Many BBS genes encode basal body or cilia proteins, suggesting that BBS is a ciliary dysfunction disorder. BBS10 (Bardet-Biedl syndrome 10), also known as chromosome 12 open reading fame 58, C12orf58 or FLJ23560, is a novel 723 amino acid protein belonging to the TCP-1 chaperonin family. BBS10 localizes to the basal body of primary cilium and assists in protein folding upon ATP hydrolysis. Inhibition of BBS10 has been found to impair ciliogenesis, activate the glycogen synthase kinase 3 pathway and cause peroxisome proliferator-activated receptor nuclear accumulation. The gene encoding BBS10 contains two exons and maps to human chromosome 12q21.2.

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