ASIC3 anticorps (AA 342-420)

N° du produit ABIN1386699

Détail du produit anti-ASIC3 anticorps

Antigène: ASIC3 (ACCN3) (Amiloride-Sensitive Cation Channel 3 (ACCN3))

Épitope: AA 342-420

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ASIC3 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Homologie: Human,Mouse,Rat,Pig,Horse

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human ASIC3

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur ASIC3

Antigène: ASIC3 (ACCN3) (Amiloride-Sensitive Cation Channel 3 (ACCN3))

Autre désignation: ASIC3a/ASIC3 (ACCN3 Produits)

Synonymes: anticorps ACCN3, anticorps Accn3, anticorps DRASIC, anticorps SLNAC1, anticorps TNaC1, anticorps AW742291, anticorps TNAC1, anticorps amiloride-sensitive cation channel 3, anticorps acid sensing ion channel subunit 3, anticorps acid-sensing (proton-gated) ion channel 3, anticorps ACCN3, anticorps ASIC3, anticorps Asic3

Sujet:

Synonyms: ASICs3, ACCN 3, ACCN3, ASIC3_HUMAN, Acid sensing ion channel 3, Acid-sensing ion channel 3, Amiloride sensitive cation channel 3, Amiloride sensitive cation channel 3 testis, Amiloride-sensitive cation channel 3, ASIC 3, ASIC3, DRASIC, hASIC 3, hASIC3, hTNaC 1, hTNaC1, Modulatory subunit of ASIC 2a, Modulatory subunit of ASIC2a, Neuronal amiloride sensitive cation channel 3, Neuronal amiloride-sensitive cation channel 3, Proton gated cation channel subunit, SLNAC 1, SLNAC1, Testis sodium channel 1, TNaC 1, TNaC1.

Background: Cation channel with high affinity for sodium, which is gated by extracellular protons and inhibited by the diuretic amiloride. Generates a biphasic current with a fast inactivating and a slow sustained phase. In sensory neurons is proposed to mediate the pain induced by acidosis that occurs in ischemic, damaged or inflamed tissue. May be involved in hyperalgesia. May play a role in mechanoreception. Heteromeric channel assembly seems to modulate channel properties.