UNC93B1 anticorps (AA 451-550)

N° du produit ABIN1386855

Détail du produit anti-UNC93B1 anticorps

Antigène: UNC93B1 (Unc-93 Homolog B1 (UNC93B1))

Épitope: AA 451-550

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UNC93B1 est non-conjugé

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Homologie: Human,Mouse,Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human UNC93B

Isotype: IgG

Information d'application

Indications d'application: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur UNC93B1

Antigène: UNC93B1 (Unc-93 Homolog B1 (UNC93B1))

Autre désignation: UNC93B (UNC93B1 Produits)

Synonymes: anticorps UNC93, anticorps IIAE1, anticorps UNC93B, anticorps Unc-93B1, anticorps Unc93b, anticorps unc-93 homolog B1, TLR signaling regulator, anticorps unc-93 homolog B1 (C. elegans), anticorps UNC93B1, anticorps Unc93b1

Sujet:

Synonyms: IIAE1, UNC93, UNC93B, Unc-93B1, Protein unc-93 homolog B1, hUNC93B1, UNC93B1

Background: Plays an important role in innate and adaptive immunity by regulating nucleotide-sensing Toll-like receptor (TLR) signaling. Required for the transport of a subset of TLRs (including TLR3, TLR7 and TLR9) from the endoplasmic reticulum to endolysosomes where they can engage pathogen nucleotides and activate signaling cascades. May play a role in autoreactive B-cells removal.

ID gène: 81622

UniProt: Q9H1C4

Pathways: Signalisation TLR, Activation of Innate immune Response, Toll-Like Receptors Cascades