HSPB7 anticorps (AA 135-170)

N° du produit ABIN1387071

Détail du produit anti-HSPB7 anticorps

Antigène: HSPB7 (Heat Shock 27kDa Protein Family, Member 7 (Cardiovascular) (HSPB7))

Épitope: AA 135-170

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HSPB7 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human HSPB7/cvHSP

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur HSPB7

Antigène: HSPB7 (Heat Shock 27kDa Protein Family, Member 7 (Cardiovascular) (HSPB7))

Autre désignation: HSPB7 (HSPB7 Produits)

Synonymes: anticorps hspb7, anticorps MGC83758, anticorps HSPB7, anticorps cvhsp, anticorps cvHSP, anticorps 27kDa, anticorps Hsp25-2, anticorps cvHsp, anticorps heat shock protein family B (small) member 7 L homeolog, anticorps heat shock protein family B (small) member 7, anticorps heat shock protein family, member 7 (cardiovascular), anticorps hspb7.L, anticorps HSPB7, anticorps hspb7, anticorps Hspb7

Sujet:

Synonyms: cvHSP, Heat shock protein beta-7, HspB7, Cardiovascular heat shock protein

Background: The heat shock proteins (HSPs) comprise a group of highly conserved, abundantly expressed proteins with diverse functions, including the assembly and sequestering of multiprotein complexes, transportation of nascent polypeptide chains across cellular membranes and regulation of protein folding. Heat shock proteins (also known as molecular chaperones) fall into six general families: HSP 90, HSP 70, HSP 60, the small HSPs, the immunophilins and the HSP 110 family. HSPB7 (heat shock 27 kDa protein family, member 7), also known as cvHSP (cardiovascular heat shock protein) or Heat shock protein beta-7, is a member of the small HSP (sHSP) family expressed in heart and skeletal muscle. Members of the sHSP family contain a conserved C-terminal ?crystallin domain and typically function in homo- or heteromeric complexes. The sHSPs bind to denatured proteins and are responsible for preventing the aggregation of these proteins. In response to muscle fiber transformation and in muscular dystrophy, the expression levels of HSPB7 are drastically increased, suggesting that HSPB7 may be a useful target in therapeutic strategies for preventing age-related muscle wasting.

ID gène: 27129

UniProt: Q9UBY9