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C21ORF45 anticorps

MIS18A Reactivité: Humain, Souris, Rat WB, IF (p), IHC (p) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN1387140
  • Antigène Voir toutes C21ORF45 (MIS18A) Anticorps
    C21ORF45 (MIS18A) (MIS18 Kinetochore Protein Homolog A (MIS18A))
    Reactivité
    • 17
    • 16
    • 15
    • 2
    • 2
    • 2
    • 2
    • 1
    Humain, Souris, Rat
    Hôte
    • 17
    Lapin
    Clonalité
    • 17
    Polyclonal
    Conjugué
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp C21ORF45 est non-conjugé
    Application
    • 17
    • 12
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
     Réactivité croisée
    Humain, Souris, Rat
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human FASP1/C21orf45
    Isotype
    IgG
    Top Product
    Discover our top product MIS18A Anticorps primaire
  • Indications d'application
    WB 1:300-5000
    IHC-P 1:200-400
    IF(IHC-P) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Date de péremption
    12 months
  • Antigène
    C21ORF45 (MIS18A) (MIS18 Kinetochore Protein Homolog A (MIS18A))
    Autre désignation
    FASP1 (MIS18A Produits)
    Synonymes
    anticorps B28, anticorps C21orf45, anticorps C21orf46, anticorps FASP1, anticorps MIS18alpha, anticorps hMis18alpha, anticorps 2610039C10Rik, anticorps 2810018N07Rik, anticorps RGD1310778, anticorps MIS18 kinetochore protein A, anticorps MIS18A, anticorps Mis18a
    Sujet

    Synonyms: B28, C21orf46, FASP1, hMis18alpha, MaFF interacting protein, MAFIP, MIS18A, Protein Mis18 alpha, MS18A_HUMAN.

    Background: Mapping to chromosome 21, the FASP1 gene (FAPP1-associated protein 1) encodes a 233 amino acid protein that is homologous to the fission yeast protein Mis18. In yeast, Mis18 is localized to the centrosome and forms a complex with Mis16 to maintain the deacetylated state of histones specifically in the central core of centromeres. FASP1, also known as Protein Mis18-alpha and C21orf45, is required for the recruitment of CENP-A to centrosomes and is thereby essential for normal chromosome segregation during mitosis. With expression in testis, FASP1 exists as a homodimer, a heterodimer with MIS18B or is present in a complex containing other Mis18 family members. FASP1 has been shown to bind to pp5644 in Hela cells, where overexpression of pp5644 leads to inhibited growth and colony formation.

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