TFAM anticorps (AA 155-246)

N° du produit ABIN1387734

Détail du produit anti-TFAM anticorps

Antigène: TFAM (Transcription Factor A, Mitochondrial (TFAM))

Épitope: AA 155-246

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TFAM est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Souris, Rat

Homologie: Human,Dog,Cow,Sheep,Pig,Rabbit,Goat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human MtTF1

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-TFAM (ABIN1387734)

Yan, Liu, Guan, Guo: "Deferoxamine ameliorates adipocyte dysfunction by modulating iron metabolism in ob/ob mice." dans: Endocrine connections, Vol. 7, Issue 4, pp. 604-616, (2018) (PubMed).

You, Hou, Zhai, Li, Li, Zhao, Zhao: "Protective effects of PGC-1α via the mitochondrial pathway in rat brains after intracerebral hemorrhage." dans: Brain research, Vol. 1646, pp. 34-43, (2016) (PubMed).

Yan, Ji, Shi, Li, Sang: "Acute nitrogen dioxide inhalation induces mitochondrial dysfunction in rat brain." dans: Environmental research, Vol. 138, pp. 416-24, (2015) (PubMed).

Détails sur TFAM

Antigène: TFAM (Transcription Factor A, Mitochondrial (TFAM))

Autre désignation: MtTF1 (TFAM Produits)

Synonymes: anticorps tcf6, anticorps mttf1, anticorps mttfa, anticorps tcf6l1, anticorps tcf6l2, anticorps tcf6l3, anticorps mttfa-A, anticorps xl-mtTFA, anticorps MGC153358, anticorps zgc:153358, anticorps MTTF1, anticorps MTTFA, anticorps TCF6, anticorps TCF6L1, anticorps TCF6L2, anticorps TCF6L3, anticorps AI661103, anticorps Hmgts, anticorps mtTFA, anticorps tsHMG, anticorps Mttfa, anticorps transcription factor A, mitochondrial, anticorps transcription factor A, mitochondrial L homeolog, anticorps TFAM, anticorps tfam.L, anticorps tfam, anticorps Tfam

Sujet:

Synonyms: TCF6, MTTF1, MTTFA, TCF6L1, TCF6L2, TCF6L3, Transcription factor A, mitochondrial, Mitochondrial transcription factor 1, Transcription factor 6, TCF-6, Transcription factor 6-like 2, TFAM

Background: Binds to the mitochondrial light strand promoter and functions in mitochondrial transcription regulation. Required for accurate and efficient promoter recognition by the mitochondrial RNA polymerase. Promotes transcription initiation from the HSP1 and the light strand promoter by binding immediately upstream of transcriptional start sites. Is able to unwind DNA. Bends the mitochondrial light strand promoter DNA into a U-turn shape via its HMG boxes. Required for maintenance of normal levels of mitochondrial DNA. May play a role in organizing and compacting mitochondrial DNA.

ID gène: 7019

UniProt: Q00059

Pathways: Chromatin Binding