CELSR3 anticorps (AA 1601-1700)

N° du produit ABIN1387763

Détail du produit anti-CELSR3 anticorps

Antigène: CELSR3 (Cadherin EGF LAG Seven Pass G-Type Receptor 3 (CELSR3))

Épitope: AA 1601-1700

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CELSR3 est non-conjugé

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Humain

Homologie: Mouse,Rat,Dog,Cow,Sheep,Pig,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Flamingo homolog 1

Isotype: IgG

Information d'application

Indications d'application: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-CELSR3 (ABIN1387763)

Su, Zhang, Gan, Jiang, Xiao, Zou, Li, Jiang: "Deregulation of the planar cell polarity genes CELSR3 and FZD3 in Hirschsprung disease." dans: Experimental and molecular pathology, Vol. 101, Issue 2, pp. 241-248, (2016) (PubMed).

Détails sur CELSR3

Antigène: CELSR3 (Cadherin EGF LAG Seven Pass G-Type Receptor 3 (CELSR3))

Autre désignation: CELSR3/Flamingo homolog 1 (CELSR3 Produits)

Synonymes: anticorps CDHF11, anticorps EGFL1, anticorps FMI1, anticorps HFMI1, anticorps MEGF2, anticorps RESDA1, anticorps Megf2, anticorps Fmi1, anticorps flamingo, anticorps mKIAA0812, anticorps cadherin EGF LAG seven-pass G-type receptor 3, anticorps cadherin, EGF LAG seven-pass G-type receptor 3, anticorps CELSR3, anticorps Celsr3

Sujet:

Synonyms: Cadherin EGF LAG seven-pass G-type receptor 3, Cadherin family member 11, CDHF11, CELR3_HUMAN, CELSR3, EGF-like protein 1, EGFL1, Epidermal growth factor-like protein 1, Flamingo, Flamingo homolog 1, FMI1, HFMI1, MEGF2, Multiple EGF-like domains protein 2, Multiple epidermal growth factor-like domains protein 2.

Background: Drosophila Flamingo is a seven pass transmembrane cadherin that is necessary for dendritic patterning and axon guidance. Flamingo mammalian homo-logs play similar roles in neuronal development, during which they play an important role in cell-cell signaling. Cadherin EGF LAG seven pass G-type receptors (CELSRs) are multi-pass membrane proteins that belong to the G protein-coupled receptor family of proteins. Silencing CELSR2 gene ex-pression results in signficant simplification of dendritic arbors of cortical pyramidal neurons and Purkinje neurons, which may be due to branch retraction. In mouse, CELSR1, CELSR2 and CELSR3 are expressed in the nervous system at early developmental stages, and show expression patterns in the developing CNS. CELSR2 is distributed at intercellular boundaries in the whisker and on processes of neuronal cells such as hippocampal pyramidal cells, Purkinje cells and olfactory neurons.

ID gène: 1951

UniProt: Q9NYQ7