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TANC1 anticorps (AA 31-130) (FITC)

TANC1 Reactivité: Humain IF (cc), IF (p) Hôte: Lapin Polyclonal FITC
N° du produit ABIN1388900
  • Antigène Voir toutes TANC1 Anticorps
    TANC1 (Tetratricopeptide Repeat, Ankyrin Repeat and Coiled-Coil Containing 1 (TANC1))
    Épitope
    • 14
    • 2
    • 1
    • 1
    AA 31-130
    Reactivité
    • 18
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 18
    Lapin
    Clonalité
    • 18
    Polyclonal
    Conjugué
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp TANC1 est conjugé à/à la FITC
    Application
    • 12
    • 12
    • 4
    • 4
    • 3
    • 3
    • 3
    • 1
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Homologie
    Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human TANC1
    Isotype
    IgG
    Top Product
    Discover our top product TANC1 Anticorps primaire
  • Indications d'application
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    TANC1 (Tetratricopeptide Repeat, Ankyrin Repeat and Coiled-Coil Containing 1 (TANC1))
    Autre désignation
    TANC1 (TANC1 Produits)
    Synonymes
    anticorps ROLSB, anticorps TANC, anticorps 1200003E16Rik, anticorps Tanc, anticorps mKIAA1728, anticorps tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1, anticorps TANC1, anticorps Tanc1
    Sujet

    Synonyms: ROLSB, Protein TANC1, Rolling pebbles homolog B, TANC, Tanc1, TANC1_HUMAN, Tetratricopeptide repeat ankyrin repeat and coiled coil containing 1, Tetratricopeptide repeat ankyrin repeat and coiled coil domain containing protein 1, TPR domain ankyrin repeat and coiled coil containing.

    Background: TANC (tetratricopeptide repeat, ankyrin repeat and coiled-coil domain-containing protein), also known as TANC1, is a 1,861 amino acid postsynaptic cell membrane protein that contains eleven ANK repeats, three TPR repeats and belongs to the TANC family. Considered a scaffolding component in the postsynaptic density, TANC interacts with TNIK, SAPAP1, Alpha-internexin, CaMKII, NMDA 2 and GluR-1. It is also thought that TANC interacts directly with SAP 97, PSD-95 and Homer. Upon stimulation by Rap 2, MINK1 and TNIK may phosphorylate TANC. The TANC gene encodes two alternatively spliced isoforms, contains approximately 264,025 bases and maps to human chromosome 2q24.2. Making up approximately 8 % of the human genome, chromosome 2 consists of 237 million bases and encodes over 1,400 genes. A number of genetic diseases are linked to genes on chromosome 2 including Harlequin icthyosis, sitosterolemia and Alstr syndrome.

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