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Chromosome 11open Reading Frame 9 (C11orf9) (AA 401-500) anticorps (Alexa Fluor 488)

C11orf9 Reactivité: Humain, Souris, Rat WB, IF (cc), IF (p) Hôte: Lapin Polyclonal Alexa Fluor 488
N° du produit ABIN1389814
  • Antigène Voir toutes Chromosome 11open Reading Frame 9 (C11orf9) Anticorps
    Chromosome 11open Reading Frame 9 (C11orf9)
    Épitope
    • 14
    • 6
    • 3
    • 2
    • 1
    • 1
    AA 401-500
    Reactivité
    • 23
    • 21
    • 15
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 27
    Lapin
    Clonalité
    • 27
    Polyclonal
    Conjugué
    • 10
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Alexa Fluor 488
    Application
    • 21
    • 12
    • 12
    • 10
    • 4
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
     Réactivité croisée
    Humain, Souris, Rat
    Homologie
    Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human MYRF
    Isotype
    IgG
    Top Product
    Discover our top product C11orf9 Anticorps primaire
  • Indications d'application
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    Chromosome 11open Reading Frame 9 (C11orf9)
    Autre désignation
    MYRF/C11orf9 (C11orf9 Produits)
    Synonymes
    anticorps C11orf9, anticorps c11orf9, anticorps mrf, anticorps ndt80, anticorps MRF, anticorps Ndt80, anticorps pqn-47, anticorps 6030439E18, anticorps Gm1804, anticorps Gm98, anticorps Mrf, anticorps chromosome 5 open reading frame, human C11orf9, anticorps myelin regulatory factor L homeolog, anticorps myelin regulatory factor, anticorps C5H11ORF9, anticorps myrf.L, anticorps MYRF, anticorps Myrf
    Sujet

    Synonyms: MRF, Ndt80, pqn-47, C11orf9, Myelin regulatory factor, Myelin gene regulatory factor, MYRF, KIAA0954

    Background: Myelin regulatory factor: Consitutes a precursor of the transcription factor. Mediates the autocatalytic cleavage that releases the Myelin regulatory factor, N-terminal component that specifically activates transcription of central nervous system (CNS) myelin genes (PubMed:23966832). Myelin regulatory factor, C-terminal: Membrane-bound part that has no transcription factor activity and remains attached to the endoplasmic reticulum membrane following cleavage. Myelin regulatory factor, N-terminal: Transcription factor that specifically activates expression of myelin genes such as MBP, MOG, MAG and PLP1 during oligodendrocyte (OL) maturation, thereby playing a central role in oligodendrocyte maturation and CNS myelination. Specifically recognizes and binds DNA sequence 5'-CTGGYAC-3' in the regulatory regions of myelin-specific genes and directly activates their expression. Not only required during oligodendrocyte differentiation but is also required on an ongoing basis for the maintenance of expression of myelin genes and for the maintenance of a mature, viable oligodendrocyte phenotype (PubMed:23966832).

    ID gène
    745
    UniProt
    Q9Y2G1
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