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SORCS1 anticorps (AA 561-660) (Alexa Fluor 555)

SORCS1 Reactivité: Humain IF (cc), IF (p) Hôte: Lapin Polyclonal Alexa Fluor 555
N° du produit ABIN1390631
  • Antigène Voir toutes SORCS1 Anticorps
    SORCS1 (Sortilin-Related VPS10 Domain Containing Receptor 1 (SORCS1))
    Épitope
    • 14
    • 10
    • 7
    • 5
    • 4
    AA 561-660
    Reactivité
    • 35
    • 2
    Humain
    Hôte
    • 35
    Lapin
    Clonalité
    • 35
    Polyclonal
    Conjugué
    • 8
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp SORCS1 est conjugé à/à la Alexa Fluor 555
    Application
    • 18
    • 17
    • 13
    • 12
    • 12
    • 3
    • 3
    • 2
    • 1
    • 1
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Homologie
    Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human SORCS1
    Isotype
    IgG
    Top Product
    Discover our top product SORCS1 Anticorps primaire
  • Indications d'application
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    SORCS1 (Sortilin-Related VPS10 Domain Containing Receptor 1 (SORCS1))
    Autre désignation
    SORCS1 (SORCS1 Produits)
    Synonymes
    anticorps hSorCS, anticorps Sorcs, anticorps mSorCS, anticorps sortilin related VPS10 domain containing receptor 1, anticorps sortilin-related VPS10 domain containing receptor 1, anticorps SORCS1, anticorps Sorcs1
    Sujet

    Synonyms: SorCS 1, SORCS, SORCS-1, SORCS receptor 1, Sortilin related VPS10 domain containing receptor 1, VPS10 domain containing receptor SorCS1, VPS10 domain receptor protein SORCS 1, VPS10 domain receptor protein SORCS, VPS10 domain receptor protein SORCS1, VPS10 domain receptor SorCS, FLJ41758, FLJ43475, FLJ44957, hSorCS, OTTHUMP00000058855, SORC1_HUMAN.

    Background: There are three sorCS genes that have diverse, partially overlapping functions in the central nervous system. In the developing and mature central nervous system, the homologous SorCS1 and SorCS2 genes and the SorCS3 gene are expressed in a combinatorial, non-overlapping pattern. SorCS proteins show homology to the mosaic receptor SorLA and the neurotensin receptor sortilin, based on a common VPS10 domain, which is the hallmark of the SorCS receptor family. SorCS1 is a type 1 receptor containing a VPS10P domain and a leucine-rich domain. Alternative splicing of human SorCS1 results in four isoforms with different cytoplasmic tails and differential expression in tissues. Human SorCS1 is detected in fetal and infant brain and in fetal retina. Alternative splicing of murine SorCS1 also results in four isoforms. Murine isoform 1 is highly expressed in brain and at lower levels in heart, liver and kidney. It is detected in newborn mouse brain and in adult olfactory bulb and cerebral cortex. Murine isoform 2 is highly expressed in liver and at lower levels in heart, brain, kidney and testis.

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