Tel:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@anticorps-enligne.fr

EN2 anticorps (AA 281-333) (Biotin)

EN2 Reactivité: Humain, Souris WB, ELISA, IHC (p), IHC (fro) Hôte: Lapin Polyclonal Biotin
N° du produit ABIN1391947
  • Antigène Voir toutes EN2 Anticorps
    EN2 (Engrailed Homeobox 2 (EN2))
    Épitope
    • 18
    • 14
    • 13
    • 5
    • 1
    AA 281-333
    Reactivité
    • 56
    • 33
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain, Souris
    Hôte
    • 53
    • 2
    • 1
    Lapin
    Clonalité
    • 54
    • 2
    Polyclonal
    Conjugué
    • 24
    • 6
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp EN2 est conjugé à/à la Biotin
    Application
    • 50
    • 30
    • 13
    • 13
    • 9
    • 7
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
     Réactivité croisée
    Humain, Souris
    Homologie
    Rat,Dog,Sheep,Pig
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human EN2/Engrailed 2
    Isotype
    IgG
    Top Product
    Discover our top product EN2 Anticorps primaire
  • Indications d'application
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C for 12 months.
    Date de péremption
    12 months
  • De Paoli, Gogalic, Sauer, Preininger, Pandha, Simpson, Horvath, Marquette: "Multiplatform Biomarker Discovery for Bladder Cancer Recurrence Diagnosis." dans: Disease markers, Vol. 2016, pp. 4591910, (2016) (PubMed).

  • Antigène
    EN2 (Engrailed Homeobox 2 (EN2))
    Autre désignation
    EN2/Engrailed 2 (EN2 Produits)
    Synonymes
    anticorps EN2, anticorps en, anticorps en2, anticorps BB131122, anticorps En-2, anticorps RGD1561842, anticorps Gg-En-2, anticorps engrailed homeobox 2, anticorps engrailed homeobox, anticorps engrailed 2, anticorps EN2, anticorps en, anticorps En2
    Sujet

    Synonyms: Homeobox protein engrailed-2, Homeobox protein en-2, Hu-En-2, EN2

    Background: The engrailed-2 gene, EN2, a murine homolog of the Drosophila homeobox gene engrailed (EN), is required for midbrain and cerebellum development and dorsal/ventral patterning of the limbs as well as apical ectodermal ridge formation. In Drosophila, the EN gene plays an important role during development in segmentation, where it is required for the formation of posterior compartments. Human EN-1 and EN-2 are homeodomain-containing proteins and have been implicated in the control of pattern formation during development of the central nervous system. Different mutations in the mouse homologs, EN-1 and EN-2, produce different developmental defects that frequently are lethal. EN-1 is highly expressed by essentially all dopaminergic neurons in the substantia nigra and ventral tegmentum. EN-1 and EN-2 regulate expression of a-synuclein, a gene that is genetically linked to Parkinson?s disease. During early brain development mouse EN-2 is expressed in a broad band across most of the mid-hindbrain region. EN-2 is also expressed in mouse myoblasts and has been assiciated with cerebellar hypoplasia.

    ID gène
    2020
    UniProt
    P19622
Vous êtes ici:
Support technique