LRRTM3 anticorps (AA 31-120) (Alexa Fluor 555)

N° du produit ABIN1392059

Détail du produit anti-LRRTM3 anticorps (Alexa Fluor 555)

Antigène: LRRTM3 (Leucine Rich Repeat Transmembrane Neuronal 3 (LRRTM3))

Épitope: AA 31-120

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LRRTM3 est conjugé à/à la Alexa Fluor 555

Application: Western Blotting (WB), Flow Cytometry (FACS)

Réactivité croisée: Souris

Homologie: Human,Rat,Cow,Sheep,Pig,Chicken,Rabbit,Monkey

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human LRRTM3

Isotype: IgG

Information d'application

Indications d'application: FCM 1:20-100

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur LRRTM3

Antigène: LRRTM3 (Leucine Rich Repeat Transmembrane Neuronal 3 (LRRTM3))

Autre désignation: LRRTM3 (LRRTM3 Produits)

Synonymes: anticorps 9630044H04Rik, anticorps leucine rich repeat transmembrane neuronal 3, anticorps LRRTM3, anticorps lrrtm3, anticorps Lrrtm3

Sujet:

Synonyms: Leucine rich repeat transmembrane neuronal protein 3, Leucine-rich repeat transmembrane neuronal protein 3, LRRT3_HUMAN, Lrrtm3, MGC131810, PRO1693, UNQ803.

Background: The leucine-rich (LRR) repeat is a 20-30 amino acid motif that forms a hydrophobic Alpha/Beta horseshoe fold, allowing it to accommodate several leucine residues within a tightly packed core. All LRR repeats contain a variable segment and a highly conserved segment, the latter of which accounts for 11 or 12 residues of the entire LRR motif. The LRRTM protein family plays a role in the regulation of various cellular events during nervous system development. Localizing predominantly to the nervous system, LRRTM family members are known to exhibit synaptogenic activity. LRRTM3 (leucine rich repeat transmembrane neuronal 3) is a 581 amino acid single-pass type I membrane protein belonging to the LRRTM family. LRRTM3 is involved in the development and maintenance of the vertebrate nervous system, and contains ten LRR repeats. Expressed in neuronal tissues, LRRTM3 is encoded by a gene that maps to a region of chromosome 10 that has been linked to late-onset Alzheimer disease and elevated plasma Beta-Amyloid. As a result of alternative splicing events, two LRRTM3 isoforms exist.

Pathways: Synaptic Membrane