NR2E3 anticorps (AA 1-100) (Biotin)

N° du produit ABIN1392067

Détail du produit anti-NR2E3 anticorps (Biotin)

Antigène: NR2E3 (Nuclear Receptor Subfamily 2, Group E, Member 3 (NR2E3))

Épitope: AA 1-100

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NR2E3 est conjugé à/à la Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Homologie: Human,Mouse,Rat,Cow,Sheep

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human NR2E3

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur NR2E3

Antigène: NR2E3 (Nuclear Receptor Subfamily 2, Group E, Member 3 (NR2E3))

Autre désignation: NR2E3 (NR2E3 Produits)

Synonymes: anticorps ESCS, anticorps PNR, anticorps RNR, anticorps RP37, anticorps rd7, anticorps LOC100228348, anticorps A930035N01Rik, anticorps wu:fj55b07, anticorps zgc:103631, anticorps nuclear receptor subfamily 2 group E member 3, anticorps nuclear receptor subfamily 2, group E, member 3, anticorps NR2E3, anticorps Nr2e3, anticorps nr2e3

Sujet:

Synonyms: ESCS, ESCS, NR2 E3, Nr2e3, NR2E3_HUMAN, Nuclear receptor subfamily 2 group E member 3, Photoreceptor specic nuclear receptor, Photoreceptor-specic nuclear receptor antibody PNR, Rd 7, rd7, Retina specic nuclear receptor, Retina-specic nuclear receptor, Retinal degeneration 7, Retinal degeneration 7, RNR, RP37.

Background: Photoreceptor-specific nuclear receptor, also known as NR2E3 or PNR, belongs to a large family of nuclear hormone receptor transcription factors. The proteins belonging to this family are characterized by discrete domains functioning in DNA and ligand binding. NR2E3 has a role in regulating the signaling pathway elemental to the photoreceptor cell function and in regulating pathways involved in embryonic development. NR2E3 is an eye specific nuclear protein found in the outer nuclear layer of the adult retina (where the nuclei of cone and rod photoreceptors are located). Defects in this gene encoding for the protein, which localizes to chromosome 15q22.32, cause enhanced S cone syndrome.

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway