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RAPGEF2 anticorps (AA 501-600) (Biotin)

RAPGEF2 Reactivité: Humain WB, ELISA, IHC (p), IHC (fro) Hôte: Lapin Polyclonal Biotin
N° du produit ABIN1392121
  • Antigène Voir toutes RAPGEF2 Anticorps
    RAPGEF2 (Rap Guanine Nucleotide Exchange Factor (GEF) 2 (RAPGEF2))
    Épitope
    • 14
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 501-600
    Reactivité
    • 29
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 27
    • 2
    Lapin
    Clonalité
    • 28
    • 1
    Polyclonal
    Conjugué
    • 13
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp RAPGEF2 est conjugé à/à la Biotin
    Application
    • 23
    • 13
    • 13
    • 9
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Homologie
    Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Chicken,Rabbit
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human RAPGEF2
    Isotype
    IgG
    Top Product
    Discover our top product RAPGEF2 Anticorps primaire
  • Indications d'application
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C for 12 months.
    Date de péremption
    12 months
  • Antigène
    RAPGEF2 (Rap Guanine Nucleotide Exchange Factor (GEF) 2 (RAPGEF2))
    Autre désignation
    RAPGEF2/PDZ-GEF1 (RAPGEF2 Produits)
    Synonymes
    anticorps MGC83978, anticorps RAPGEF2, anticorps fa11h07, anticorps wu:fa11h07, anticorps CNrasGEF, anticorps NRAPGEP, anticorps PDZ-GEF1, anticorps PDZGEF1, anticorps RA-GEF, anticorps Rap-GEP, anticorps nRap GEP, anticorps 5830453M24Rik, anticorps CNRasGEF, anticorps Pdzgef1, anticorps RA-GEF-1, anticorps mKIAA0313, anticorps nRapGEP, anticorps Rap guanine nucleotide exchange factor 2, anticorps Rap guanine nucleotide exchange factor 2 L homeolog, anticorps Rap guanine nucleotide exchange factor (GEF) 2, anticorps RAPGEF2, anticorps rapgef2.L, anticorps rapgef2, anticorps Rapgef2
    Sujet

    Synonyms: KIAA0313, Neural RAP guanine nucleotide exchange protein, nRap GEP, NRAPGEP, PDZ domain containing guanine nucleotide exchange factor 1, PDZ domain-containing guanine nucleotide exchange factor 1, PDZ GEF1, PDZ-GEF1, PDZGEF1, RA GEF, RA-GEF, Rap guanine nucleotide exchange factor 2, Rapgef2, RPGF2_HUMAN.

    Background: PDZ-GEF1 is a 1,499 amino acid cell membrane protein that functions as a guanine nucleotide exchange factor for Rap 1A, Rap 1B and Rap 2B GTPases. Expressed at highest levels in brain, PDZ-GEF1 is found at low levels in placenta, heart, lung and kidney, and undergoes post-translational phosphorylation following DNA damage. PDZ-GEF1 interacts with MAGI-2 and contains one Ras-GEF domain, a Ras-associating domain, one PDZ (DHR) domain, a single N-terminal Ras-GEF domain and a cyclic nucleotide-binding domain. The gene encoding PDZ-GEF1 maps to human chromosome 4q32.1.

    Pathways
    Neurotrophin Signaling Pathway
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