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APH1B anticorps (AA 51-150) (Biotin)

Aph1b Reactivité: Souris WB, ELISA, IHC (fro), IHC (p) Hôte: Lapin Polyclonal Biotin
N° du produit ABIN1392469
  • Antigène Voir toutes APH1B (Aph1b) Anticorps
    APH1B (Aph1b) (Anterior Pharynx Defective 1 Homolog B (Aph1b))
    Épitope
    • 14
    • 4
    • 2
    • 1
    • 1
    • 1
    AA 51-150
    Reactivité
    • 19
    • 10
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    Souris
    Hôte
    • 24
    Lapin
    Clonalité
    • 24
    Polyclonal
    Conjugué
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp APH1B est conjugé à/à la Biotin
    Application
    • 21
    • 13
    • 13
    • 8
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
     Réactivité croisée
    Souris
    Homologie
    Human,Rat,Dog,Cow,Sheep,Pig
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human Aph-1b
    Isotype
    IgG
    Top Product
    Discover our top product Aph1b Anticorps primaire
  • Indications d'application
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C for 12 months.
    Date de péremption
    12 months
  • Antigène
    APH1B (Aph1b) (Anterior Pharynx Defective 1 Homolog B (Aph1b))
    Autre désignation
    Aph-1b (Aph1b Produits)
    Synonymes
    anticorps APH-1B, anticorps PRO1328, anticorps PSFL, anticorps TAAV688, anticorps APH-1B', anticorps 2310057K14Rik, anticorps Aph1c, anticorps aph-1 homolog B, gamma-secretase subunit, anticorps aph-1 homolog B, gamma secretase subunit, anticorps aph1 homolog B, gamma secretase subunit, anticorps APH1B, anticorps Aph1b
    Sujet

    Synonyms: PSFL, APH-1B, PRO1328, TAAV688, Gamma-secretase subunit APH-1B, Aph-1beta, Presenilin-stabilization factor-like, APH1B, UNQ688/PRO1328

    Background: Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral proteins such as Notch receptors and APP (beta-amyloid precursor protein). It probably represents a stabilizing cofactor for the presenilin homodimer that promotes the formation of a stable complex. Probably present in a minority of gamma-secretase complexes compared to APH1A.

    ID gène
    83464
    UniProt
    Q8WW43
    Pathways
    Signalisation Notch, Neurotrophin Signaling Pathway
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