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AFF2 anticorps (AA 1-80) (Alexa Fluor 350)

AFF2 Reactivité: Humain WB, IF (cc), IF (p) Hôte: Lapin Polyclonal Alexa Fluor 350
N° du produit ABIN1392837
  • Antigène Voir toutes AFF2 Anticorps
    AFF2 (AF4/FMR2 Family, Member 2 (AFF2))
    Épitope
    • 14
    • 7
    • 6
    • 6
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    AA 1-80
    Reactivité
    • 46
    • 10
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 45
    • 1
    Lapin
    Clonalité
    • 45
    • 1
    Polyclonal
    Conjugué
    • 12
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Cet anticorp AFF2 est conjugé à/à la Alexa Fluor 350
    Application
    • 35
    • 22
    • 12
    • 12
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Homologie
    Human,Mouse,Rat,Dog,Cow,Pig,Horse
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human AFF2
    Isotype
    IgG
    Top Product
    Discover our top product AFF2 Anticorps primaire
  • Indications d'application
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    AFF2 (AF4/FMR2 Family, Member 2 (AFF2))
    Autre désignation
    FMR2/AFF2 (AFF2 Produits)
    Synonymes
    anticorps FMR2, anticorps FMR2P, anticorps FRAXE, anticorps MRX2, anticorps OX19, anticorps Fmr2, anticorps Ox19, anticorps Oxh, anticorps AF4/FMR2 family member 2, anticorps AF4/FMR2 family, member 2, anticorps AFF2, anticorps Aff2
    Sujet

    Synonyms: AF4/FMR2 family member 2, AF4/FMR2 family, member 2, AFF2, AFF2_HUMAN, FMR2, FMR2P, Fragile X E mental retardation syndrome protein, fragile X mental retardation 2, Fragile X mental retardation 2 protein, fragile X mental retardation gene associated with FRAXE, FRAXE, mild or borderline mental retardation, MRX2, OX19, Protein FMR-2, Protein Ox19.

    Background: FMR2 is a 1311 amino acid nuclear protein belonging to the AF4 family. Expressed in the brain, placenta and lung, FMR2 exists as two isoforms produced by alternative splicing. Defects in the gene that encodes FMR2 have been found to be a cause of FRAXE, an X-linked form of mental retardation. Individuals expressing the FRAXE site also have more than two-hundred copies of a GCC repeat adjacent to CpG island, compared to six to thirty-five copies of the GCC repeat in a normal individual. It is believed that loss of FMR2 expression causes this GCC expansion of the FRAXE site.

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