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CRBN anticorps (AA 210-288) (Alexa Fluor 488)

CRBN Reactivité: Souris, Rat IF (cc), IF (p) Hôte: Lapin Polyclonal Alexa Fluor 488
N° du produit ABIN1392916
  • Antigène Voir toutes CRBN Anticorps
    CRBN (Cereblon (CRBN))
    Épitope
    • 14
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 210-288
    Reactivité
    • 19
    • 18
    • 11
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Souris, Rat
    Hôte
    • 23
    • 2
    Lapin
    Clonalité
    • 25
    Polyclonal
    Conjugué
    • 12
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CRBN est conjugé à/à la Alexa Fluor 488
    Application
    • 12
    • 12
    • 11
    • 6
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
     Réactivité croisée
    Souris, Rat
    Homologie
    Human,Dog,Cow,Sheep,Pig,Horse,Rabbit,Zebrafish
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human CRBN
    Isotype
    IgG
    Top Product
    Discover our top product CRBN Anticorps primaire
  • Indications d'application
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    CRBN (Cereblon (CRBN))
    Autre désignation
    CRBN (CRBN Produits)
    Synonymes
    anticorps zgc:92404, anticorps mrt2a, anticorps F3N11.21, anticorps MRT2, anticorps MRT2A, anticorps 2610203G15Rik, anticorps 2900045O07Rik, anticorps AF229032, anticorps AW108261, anticorps piL, anticorps cereblon, anticorps ATP-dependent protease La (LON) domain protein, anticorps crbn, anticorps CRBN, anticorps AT2G25740, anticorps Crbn
    Sujet

    Synonyms: Cereblon, DKFZp781K0715, MGC27358, MRT2A, OTTHUMP00000209555, piL, Protein cereblon, Protein x 0001, 2610203G15Rik, 2900045O07Rik, AF229032, AW108261, CRBN_HUMAN.

    Background: CRBN is a 442 amino acid protein which is highly concentrated in human brain tissue. CRBN functions are thought to be related to energy metabolism, learning and memory. Localized to the cytoplasm, CRBN acts as a protease in mitochondria and is thought to regulate the assembly of KCNT1, as well as the surface expression of KCNT1 in brain regions known to affect memory and learning, such as the hippocampus. The gene encoding CRBN belongs to a family of ATP-dependent lon proteases that play a role in membrane trafficking and proteolysis. Defects in the CRBN gene are associated with mild mental retardation.

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