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MAP3K4 anticorps (AA 1351-1450) (Biotin)

MAP3K4 Reactivité: Humain ELISA, IHC (p), IHC (fro) Hôte: Lapin Polyclonal Biotin
N° du produit ABIN1393891
  • Antigène Voir toutes MAP3K4 Anticorps
    MAP3K4 (Mitogen-Activated Protein Kinase Kinase Kinase 4 (MAP3K4))
    Épitope
    • 14
    • 7
    • 7
    • 6
    • 6
    • 6
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1351-1450
    Reactivité
    • 50
    • 8
    • 5
    Humain
    Hôte
    • 47
    • 3
    Lapin
    Clonalité
    • 46
    • 4
    Polyclonal
    Conjugué
    • 21
    • 6
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp MAP3K4 est conjugé à/à la Biotin
    Application
    • 30
    • 28
    • 23
    • 13
    • 13
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Homologie
    Human,Mouse,Rat,Dog,Cow,Pig,Horse,Chicken,Rabbit
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human MAP3K4/MEK kinase-4
    Isotype
    IgG
    Top Product
    Discover our top product MAP3K4 Anticorps primaire
  • Indications d'application
    IHC-P 1:200-400
    IHC-F 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C for 12 months.
    Date de péremption
    12 months
  • Antigène
    MAP3K4 (Mitogen-Activated Protein Kinase Kinase Kinase 4 (MAP3K4))
    Autre désignation
    MAP3K4/MEK kinase-4 (MAP3K4 Produits)
    Synonymes
    anticorps MAPKKK4, anticorps MEKK4, anticorps MTK1, anticorps PRO0412, anticorps D17Rp17, anticorps D17Rp17e, anticorps MEKK 4, anticorps Mek4b, anticorps Mekk4, anticorps RP17, anticorps Rp17a, anticorps Tas, anticorps mKIAA0213, anticorps mitogen activated protein kinase kinase kinase 4, anticorps mitogen-activated protein kinase kinase kinase 4, anticorps Map3k4, anticorps MAP3K4
    Sujet

    Synonyms: FLJ42439, KIAA0213, M3K4_HUMAN, MAP three kinase 1, MAP3K4, MAPK/ERK kinase kinase 4, MAPKKK4 antibodyMEK kinase 4, MEKK 4, MEKK4, Mitogen-activated protein kinase kinase kinase 4, MTK1, PRO0412, RP3-473J16.4

    Background: Mitogen-activated protein (MAP) kinase cascades are activated by various extracellular stimuli including growth factors. The MEK kinases (also designated MAP kinase kinase kinases, MKKKs, MAP3Ks or MEKKs) phosphorylate and thereby activate the MEKs (also called MAP kinase kinases or MKKs), including ERK, JNK and p38. These activated MEKs in turn phosphorylate and activate the MAP kinases. The MEK kinases include Raf-1, Raf-B, Mos, MEK kinase-1, MEK kinase-2, MEK kinase-3, MEK kinase-4, ASK 1 (MEK kinase-5) and MAP3K6 (MEK kinase-6). MEK kinase-1 has been shown to phosphorylate MEK-1 via Raf-independent pathway. Evidence suggests that MEK-3 is preferentially activated by MEK kinase-3 and that MEK-4 is activated by both MEK kinase-2 and MEK kinase-3. MEK kinase-4 has been shown to specifically activate the JNK path-way. ASK1 activates both MEK-4 and MEK-3/MEK-6 pathways.

    Pathways
    Signalisation MAPK
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