HUNK anticorps (AA 71-115) (Alexa Fluor 555)
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- Antigène Tous les produits HUNK
- HUNK (Hormonally Up-Regulated Neu-Associated Kinase (HUNK))
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Épitope
- AA 71-115
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp HUNK est conjugé à/à la Alexa Fluor 555
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Application
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Homologie
- Human,Mouse,Rat,Cow,Sheep,Pig,Rabbit
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human Serine/threonine-protein kinase MAK-V
- Isotype
- IgG
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- Indications d'application
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- HUNK (Hormonally Up-Regulated Neu-Associated Kinase (HUNK))
- Autre désignation
- Serine/threonine-protein kinase MAK-V (HUNK Produits)
- Synonymes
- anticorps HUNK, anticorps TPT1P, anticorps Bstk1, anticorps Mak-v, anticorps RGD1565091, anticorps hormonally up-regulated Neu-associated kinase, anticorps hormonally upregulated Neu-associated kinase, anticorps HUNK, anticorps Hunk
- Sujet
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Synonyms: B19, Hormonally up-regulated neu tumor-associated kinase, Hormonally upregulated neu associated, Hormonally upregulated neu associated kinase, Hormonally upregulated neu tumor associated kinase, HUNK, HUNK_HUMAN, MAKV, Serine/threonine-protein kinase MAK-V.
Background: The HUNK (hormonally upregulated Neu-associated kinase) protein, also designated MAK-V in mouse, has been identified as a novel SNF1-related serine/threonine kinase. The human HUNK gene localizes to chromosome 21q22 and encodes a protein with nucleocytoplasmic distribution and localizes to the centrosome. Overexpression of the HUNK protein associates with approximately 50 % of breast carcinomas, and may provide diagnostic-prognostic value as a molecular marker. Serine/threonine-protein kinase SNF1-like kinase 2 (SIK) phosphorylates Ser-794 of IRS1 in insulin-stimulated adipocytes, which may modulate the efficiency of insulin signal transduction. SIK is activated by phosphorylation on Thr-175 by STK11 in complex with STE20-related adapter- and CAB39.
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