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Serotonin Receptor 2B anticorps (AA 1-100) (Alexa Fluor 555)

HTR2B Reactivité: Humain WB, IF (cc), IF (p) Hôte: Lapin Polyclonal Alexa Fluor 555
N° du produit ABIN1394867
  • Antigène Voir toutes Serotonin Receptor 2B (HTR2B) Anticorps
    Serotonin Receptor 2B (HTR2B)
    Épitope
    • 14
    • 7
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-100
    Reactivité
    • 57
    • 14
    • 13
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Humain
    Hôte
    • 53
    • 4
    Lapin
    Clonalité
    • 54
    • 3
    Polyclonal
    Conjugué
    • 31
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Serotonin Receptor 2B est conjugé à/à la Alexa Fluor 555
    Application
    • 39
    • 16
    • 13
    • 12
    • 12
    • 11
    • 9
    • 3
    • 2
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
     Réactivité croisée
    Humain
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human 5HT2B Receptor/SR-2B
    Isotype
    IgG
    Top Product
    Discover our top product HTR2B Anticorps primaire
  • Indications d'application
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    Serotonin Receptor 2B (HTR2B)
    Autre désignation
    5HT2B Receptor/SR-2B (HTR2B Produits)
    Synonymes
    anticorps 5-HT2B, anticorps 5HT2B, anticorps 5htr2b, anticorps HTR2B, anticorps 5ht2b, anticorps zgc:194094, anticorps zgc:194119, anticorps AJ012488, anticorps AV377389, anticorps 5-HT(2B), anticorps 5-hydroxytryptamine receptor 2B, anticorps 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled, anticorps 5-hydroxytryptamine (serotonin) receptor 2B, anticorps HTR2B, anticorps htr2b, anticorps Htr2b
    Sujet

    Synonyms: 5 HT 2B, 5 HT 2B receptor, 5 HT2B, 5 HT2B, 5 hydroxytryptamine serotonin receptor 2B, 5 hydroxytryptamine serotonin receptor 2B G protein coupled, 5 hydroxytryptamine 2B receptor, 5 hydroxytryptamine receptor 2B, 5-HT-2B, 5-HT2B, 5-hydroxytryptamine receptor 2B, 5HT2B, 5HT2B_HUMAN, 5HT2F, Htr 2b, Htr2b, NP75 protein, SEROTONIN 5HT2B RECEPTOR, Serotonin receptor 2B, Stomach fundus serotonin receptor.

    Background: Serotonin (also designated 5-hydroxytryptamine or 5-HT) is a molecule that functions as a neurotransmitter, a hormone and a mitogen, and it is predominantly expressed in the gut, platelets and central nervous system (CNS). In the CNS, serotonin modulates several processes, including anxiety, sleep, appetite, behavior and drug abuse. In platelets and gut, serotonin plays a major role in cardiovascular function and motility of the gastrointestinal tract, respectively. Serotonin mediates its effects through several of G protein coupled receptors, designated 5-HT receptors or alternatively SR receptors. The SR-2 receptors are comprised of three subtypes, SR-2A, SR-2B and SR-2C, which activate phospholipase C and release intracellular stores of calcium in response to serotonin. SR-2A has a specific role in tracheal smooth muscle contraction, bronchoconstriction and mediating aldosterone production, and it is also thought to play a role in several psychiatric disorders, including depression and schizophrenia. SR-2B is expressed in embryonic and adult cardiovascular tissues, gut and brain and plays an important role in the pathology of cardiac disorders. SR-2C is thought to mediate the effects of atypical antipsychotic drugs.

    Pathways
    Signalistation JAK/STAT, Inositol Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of Carbohydrate Metabolic Process
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