KCNF1 anticorps (AA 161-260) (Alexa Fluor 488)

N° du produit ABIN1395580

Détail du produit anti-KCNF1 anticorps (Alexa Fluor 488)

Antigène: KCNF1 (Potassium Voltage-Gated Channel, Subfamily F, Member 1 (KCNF1))

Épitope: AA 161-260

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KCNF1 est conjugé à/à la Alexa Fluor 488

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Réactivité croisée: Souris

Homologie: Human,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit,Guinea Pig

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human KCNF1

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur KCNF1

Antigène: KCNF1 (Potassium Voltage-Gated Channel, Subfamily F, Member 1 (KCNF1))

Autre désignation: KCNF1 (KCNF1 Produits)

Sujet:

Synonyms: IK 8, IK8, KCNF 1, KCNF, Kcnf1, KCNF1_HUMAN, kH 1, kH1, KV5.1, Potassium voltage-gated channel subfamily F member 1, MGC33316, Potassium channel KH1, Potassium channel Kv5.1, Potassium voltage gated channel subfamily F member 1, Potassium voltage-gated channel subfamily F member 1, Voltage gated potassium channel subunit Kv5.1, Voltage-gated potassium channel subunit Kv5.1.

Background: KCNF1 is a multi-pass membrane-bound protein that acts as an ion channel and is generally expressed as a heterotetramer of potassium channeling proteins. Formerly known as kH1, KCNF1 is usually found as a heteromer with three other potassium channel proteins, KCNG3, KV6.3 and KCNV2. As a potassium channel protein, KCNF1 plays a role in regulating apoptosis and proliferation of pulmonary artery smooth muscle (PASM) cells. Bone morphogenetic proteins (BMPs) restrict proliferation and can induce apoptosis in normal human PASM cells and will upregulate expression of KCNF1 in PASM cells in vitro. KCNF1 is expressed in heart, brain, liver, skeletal muscle, kidney and pancreas.