HSPB2 anticorps (AA 101-182) (Alexa Fluor 647)

N° du produit ABIN1396577

Détail du produit anti-HSPB2 anticorps (Alexa Fluor 647)

Antigène: HSPB2 (Heat Shock 27kDa Protein 2 (HSPB2))

Épitope: AA 101-182

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HSPB2 est conjugé à/à la Alexa Fluor 647

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Réactivité croisée: Souris, Rat

Homologie: Human,Dog,Cow,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human HSPB2

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur HSPB2

Antigène: HSPB2 (Heat Shock 27kDa Protein 2 (HSPB2))

Autre désignation: HSPB2 (HSPB2 Produits)

Synonymes: anticorps zgc:112532, anticorps HSP27, anticorps Hs.78846, anticorps LOH11CR1K, anticorps MKBP, anticorps 27kDa, anticorps 2810021G24Rik, anticorps heat shock protein family B (small) member 2, anticorps heat shock protein, alpha-crystallin-related, b2, anticorps heat shock protein 2, anticorps HSPB2, anticorps hspb2, anticorps Hspb2

Sujet:

Synonyms: MKBP, HSP27, Hs.78846, LOH11CR1K, Heat shock protein beta-2, HspB2, DMPK-binding protein

Background: The heat shock proteins (HSPs) comprise a group of highly conserved, abundantly expressed proteins with diverse functions, including the assembly and sequestering of multi-protein complexes, transportation of nascent polypeptide chains across cellular membranes and regulation of protein folding. HSPB2 (heat shock 27 kDa protein 2), also known as HSP 27 or MKBP, is a 182 amino acid protein that belongs to the heat shock protein family and is expressed preferentially in heart and skeletal muscle. Localized to mitochondria, HSPB2 functions as an ATP-dependent chaperone protein that plays a role in the refolding of denatured proteins and may also interact with the Actin cytoskeleton and prevent apoptotic cell death. HSPB2 is abundantly expressed in several cancer cell lines, suggesting that HSPB2 may be an important factor in tumor transformation and metastasis.

ID gène: 3316

UniProt: Q16082