THRAP3 anticorps (AA 631-730) (Alexa Fluor 647)

N° du produit ABIN1397829

Détail du produit anti-THRAP3 anticorps (Alexa Fluor 647)

Antigène: THRAP3 (Thyroid Hormone Receptor Associated Protein 3 (THRAP3))

Épitope: AA 631-730

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp THRAP3 est conjugé à/à la Alexa Fluor 647

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Réactivité croisée: Humain, Rat

Homologie: Mouse,Dog,Cow,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Thrap3/TRAP150

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur THRAP3

Antigène: THRAP3 (Thyroid Hormone Receptor Associated Protein 3 (THRAP3))

Autre désignation: Thrap3 (THRAP3 Produits)

Synonymes: anticorps TRAP150, anticorps 9330151F09Rik, anticorps B230333E16Rik, anticorps Trap150, anticorps trap150, anticorps Thrap3, anticorps MGC132228, anticorps zgc:85716, anticorps thyroid hormone receptor associated protein 3, anticorps DNA cross-link repair 1A protein, anticorps thyroid hormone receptor associated protein 3 S homeolog, anticorps thyroid hormone receptor-associated protein 3, anticorps thyroid hormone receptor associated protein 3b, anticorps THRAP3, anticorps CpipJ_CPIJ018886, anticorps CpipJ_CPIJ019503, anticorps Thrap3, anticorps thrap3, anticorps thrap3.S, anticorps thrap3b

Sujet:

Synonyms: Thrap3, Thyroid hormone receptor associated protein 3, Thyroid hormone receptor-associated protein 3, Thyroid hormone receptor-associated protein complex 150 kDa component, Thyroid hormone receptor-associated protein complex,TR150_HUMAN, Trap150.

Background: In mammalian cells, transcription is regulated in part by high molecular weight coactivating complexes that mediate signaling between transcriptional activators and initiation factors. These complexes include the thyroid hormone receptor-associated protein (TRAP) complex, which interacts with thyroid receptors (TR), vitamin D receptors and other steroid receptors to facilitate hormone induced transcriptional activation. The TRAP complex consists of numerous proteins ranging in size including TRAP95, TRAP100, TRAP150, TRAP220 and TRAP230, that are characterized by the presence of a nuclear receptor recognition motif which mediates the ligand-dependent binding of TRAP proteins to the nuclear receptors. TRAP220 and TRAP100 are widely expressed and most abundantly detected in skeletal muscle, heart and placenta. TRAP95, TRAP150 and TRAP230 facilitate TR induced transcription by associating with an additional transcriptional coactivating complex SMCC (SRB and MED protein cofactor complex), which consists of various subunits that share homology with several components of the yeast transcriptional mediator complexes.

ID gène: 389541

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway