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UBE2E2 anticorps (AA 1-100) (Alexa Fluor 488)

UBE2E2 Reactivité: Humain, Rat WB, IF (cc), IF (p) Hôte: Lapin Polyclonal Alexa Fluor 488
N° du produit ABIN1398586
  • Antigène Voir toutes UBE2E2 Anticorps
    UBE2E2 (Ubiquitin-Conjugating Enzyme E2E 2 (UBE2E2))
    Épitope
    • 14
    • 10
    • 8
    • 6
    • 2
    • 2
    • 2
    AA 1-100
    Reactivité
    • 40
    • 20
    • 14
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain, Rat
    Hôte
    • 39
    • 1
    Lapin
    Clonalité
    • 39
    • 1
    Polyclonal
    Conjugué
    • 17
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp UBE2E2 est conjugé à/à la Alexa Fluor 488
    Application
    • 40
    • 19
    • 13
    • 12
    • 12
    • 5
    • 4
    • 3
    • 3
    • 2
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
     Réactivité croisée
    Humain, Rat
    Homologie
    Mouse,Cow,Sheep
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human UBE2E2
    Isotype
    IgG
    Top Product
    Discover our top product UBE2E2 Anticorps primaire
  • Indications d'application
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    UBE2E2 (Ubiquitin-Conjugating Enzyme E2E 2 (UBE2E2))
    Autre désignation
    UBE2E2 (UBE2E2 Produits)
    Synonymes
    anticorps ubch8, anticorps UBCH8, anticorps wu:fb38h07, anticorps zgc:92467, anticorps BC016265, anticorps ubiquitin-conjugating enzyme E2E 2, anticorps ubiquitin conjugating enzyme E2E 2 L homeolog, anticorps ubiquitin conjugating enzyme E2E 2, anticorps Ube2e2 protein, anticorps ubiquitin conjugating enzyme E2 E2, anticorps UBE2E2, anticorps ube2e2.L, anticorps ube2e2, anticorps Ube2e2
    Sujet

    Synonyms: UB2E2_HUMAN, UBC4/5 homolog yeast, UBCH 8, UbcH8, Ube2e2, Ubiquitin carrier protein E2, Ubiquitin conjugating enzyme E2 E2, Ubiquitin conjugating enzyme E2E 2 homologous to yeast UBC4/5, Ubiquitin conjugating enzyme E2E 2 UBC4/5 homolog yeast, Ubiquitin conjugating enzyme E2E 2, Ubiquitin protein ligase E2, Ubiquitin-conjugating enzyme E2 E2, Ubiquitin-protein ligase E2.

    Background: Ubiquitination is an important mechanism through which three classes of enzymes act in concert to target short-lived or abnormal proteins for destruction. The three classes of enzymes involved in ubiquitination are the ubiquitin-activating enzymes (E1s), the ubiquitin-conjugating enzymes (E2s) and the ubiquitin-protein ligases (E3s). The first step in the ubiquitination process requires the ATP-dependent activation of the ubiquitin C-terminus and the assembly of multi-ubiquitin chains by the E1 enzyme. The ubiquitin chain is then conjugated to the E2 enzyme to generate an intermediate ubiquitin-E2 complex. The E3 enzyme then catalyzes the transfer of ubiquitin from E2 to the appropriate protein substrate, thereby targeting that substrate for degradation. A wide range of enzymes facilitate this proteolytic ubiquitin pathway, one of which is UBE2E2 (also known as UBCH8 in human), which functions as an E2 enzyme and catalyzes the ATP-dependent covalent attachment of ubiquitin to target proteins, thereby playing an important role in protein degradation.

    ID gène
    7325
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