UBE2H anticorps (AA 101-183) (Alexa Fluor 350)

N° du produit ABIN1398687

Détail du produit anti-UBE2H anticorps (Alexa Fluor 350)

Antigène: UBE2H (Ubiquitin-Conjugating Enzyme E2H (UBE2H))

Épitope: AA 101-183

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UBE2H est conjugé à/à la Alexa Fluor 350

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Homologie: Mouse,Rat,Dog,Cow,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Ube2H/UBCH2

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur UBE2H

Antigène: UBE2H (Ubiquitin-Conjugating Enzyme E2H (UBE2H))

Autre désignation: Ube2H (UBE2H Produits)

Sujet:

Synonyms: E2 20K, Ubc H2, UBC8, UBCH 2, UBCH, UBCH2, Ube2h, UBE2H_HUMAN, Ubiquitin carrier protein H, Ubiquitin conjugating enzyme E2 H, Ubiquitin conjugating enzyme E2H UBC8 homolog yeast, Ubiquitin conjugating enzyme E2H, Ubiquitin protein ligase H, Ubiquitin-conjugating enzyme E2 H, Ubiquitin-conjugating enzyme E2-20K, Ubiquitin-protein ligase H.

Background: UBE2H, also known as UBC8, UBCH, UBCH2 or E2-20K, is a 183 amino acid protein involved in ubiquitin-mediated protein degradation. Ubiquitination is an important mechanism through which three classes of enzymes act in concert to target short-lived or abnormal proteins for destruction. The three classes of enzymes involved in ubiquitination are the ubiquitin-activating enzymes (E1s), the ubiquitin-conjugating enzymes (E2s) and the ubiquitin-protein ligases (E3s). One of several members of the ubiquitin-conjugating enzyme family, UBE2H functions as an E2 ubiquitin-conjugating enzyme that acts to catalyze the covalent attachment of ubiquitin residues to various proteins, including Histone H2A. UBE2H shares 100 % identity with its mouse counterpart and 98 % identity with its frog and zebrafish homologs, suggesting a conserved function between species. Multiple isoforms of UBE2H exist due to alternative splicing events.

ID gène: 7328