UBE2G1 anticorps (AA 101-170) (Alexa Fluor 647)

N° du produit ABIN1398696

Détail du produit anti-UBE2G1 anticorps (Alexa Fluor 647)

Antigène: UBE2G1 (Ube2g1) (Ubiquitin-Conjugating Enzyme E2G 1 (Ube2g1))

Épitope: AA 101-170

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UBE2G1 est conjugé à/à la Alexa Fluor 647

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Réactivité croisée: Rat

Homologie: Mouse,Dog,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Ube2G1/UBC7

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur UBE2G1

Antigène: UBE2G1 (Ube2g1) (Ubiquitin-Conjugating Enzyme E2G 1 (Ube2g1))

Autre désignation: Ube2G1 (Ube2g1 Produits)

Synonymes: anticorps E217K, anticorps UBC7, anticorps UBE2G, anticorps 2700059C12Rik, anticorps AI256795, anticorps AU014992, anticorps AW552068, anticorps D130023C12Rik, anticorps Ubc7, anticorps e217k, anticorps ubc7, anticorps ube2g, anticorps UB2G1, anticorps ube2g1, anticorps ubiquitin conjugating enzyme E2 G1, anticorps ubiquitin-conjugating enzyme E2G 1, anticorps ubiquitin-conjugating enzyme E2 G1, anticorps ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, yeast), anticorps ubiquitin conjugating enzyme E2 G1 S homeolog, anticorps UBE2G1, anticorps Ube2g1, anticorps EDI_082630, anticorps Bm1_26310, anticorps ube2g1, anticorps ube2g1.S

Sujet:

Synonyms: E217K, UB2G1_HUMAN, UBC 7, UBC7, UBC7 homolog yeast, UBE 2G, UBE2G, Ube2g1, Ubiquitin carrier protein G1, Ubiquitin conjugating enzyme E2 G1, Ubiquitin conjugating enzyme E2G 1 homologous to C. elegans UBC7, Ubiquitin conjugating enzyme E2G 1 UBC7 homolog C. elegans, Ubiquitin conjugating enzyme E2G 1 UBC7 homolog yeast, Ubiquitin conjugating enzyme E2G 1, Ubiquitin protein ligase G1, Ubiquitin-conjugating enzyme E2 G1, Ubiquitin-protein ligase G1.

Background: Ubiquitin is an abundant, highly conserved protein found in all eukaryotic cells either free or covalently attached to cellular proteins. The primary function of ubiquitin in mammalian systems is to clear abnormal, foreign, and improperly folded proteins by targeting them for proteosome degradation. In Saccharomyces cerevisiae, ubiquitin-like proteins include Rub1, Ula1, Uba3, Smt3, Ubc2, Ubc12 and Ubc9. Rub1 shares 53 % homology with ubiquitin and requires activation via the E2 proteins, including Ula1, Uba3 and Ubc12 in order to conjugate to substrates directed to different proteolytic systems. Ubc4 catalyzes ubiquitination of IkBa in a phosphorylation and SCFB-TRCP dependent manner. In this particular reaction, E1 first transfers ubiquitin to the E2 component Ubc4, and Ubc4 then associates with E3 ligase, which conjugates the poly-ubiquitin chain on a target protein. In this fashion, the chain tags the IkBa for degradation by a proteasome thus lifting the inhibitory effect of IkBa on NFkB and allowing NFkB to enter the nucleus.

ID gène: 7326