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UBE2J2 anticorps (AA 1-100) (Alexa Fluor 488)

UBE2J2 Reactivité: Humain WB, IF (cc), IF (p) Hôte: Lapin Polyclonal Alexa Fluor 488
N° du produit ABIN1398754
  • Antigène Voir toutes UBE2J2 Anticorps
    UBE2J2 (Ubiquitin-Conjugating Enzyme E2, J2 (UBE2J2))
    Épitope
    • 14
    • 4
    • 2
    • 2
    • 2
    • 1
    AA 1-100
    Reactivité
    • 35
    • 14
    • 8
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 32
    • 3
    Lapin
    Clonalité
    • 35
    Polyclonal
    Conjugué
    • 15
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp UBE2J2 est conjugé à/à la Alexa Fluor 488
    Application
    • 27
    • 12
    • 12
    • 8
    • 7
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
     Réactivité croisée
    Humain
    Homologie
    Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human UBE2J2
    Isotype
    IgG
    Top Product
    Discover our top product UBE2J2 Anticorps primaire
  • Indications d'application
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    UBE2J2 (Ubiquitin-Conjugating Enzyme E2, J2 (UBE2J2))
    Autre désignation
    UBE2J2 (UBE2J2 Produits)
    Synonymes
    anticorps NCUBE-2, anticorps NCUBE2, anticorps PRO2121, anticorps 1200007B18Rik, anticorps 2400008G19Rik, anticorps 5730472G04Rik, anticorps AL022923, anticorps Ubc6, anticorps Ubc6p, anticorps zgc:162164, anticorps ubiquitin conjugating enzyme E2 J2, anticorps ubiquitin-conjugating enzyme E2J 2, anticorps ubiquitin-conjugating enzyme E2, J2, anticorps ubiquitin-conjugating enzyme E2 J2, anticorps ubiquitin-conjugating enzyme E2, J2 (UBC6 homolog, yeast), anticorps ubiquitin conjugating enzyme E2 J2 L homeolog, anticorps UBE2J2, anticorps Ube2j2, anticorps LOC5574000, anticorps CpipJ_CPIJ008956, anticorps ube2j2, anticorps uce2, anticorps ube2j2.L, anticorps LOC100067387
    Sujet

    Synonyms: NCUBE-2, NCUBE2, Non-canonical ubiquitin-conjugating enzyme 2, UB2J2_HUMAN, UBC6, UBC6 homolog, ube2j2, Ubiquitin-conjugating enzyme E2 J2.

    Background: Ubiquitination is an important molecular mechanism by which abnormal or short-lived proteins are targeted for degradation by the concerted efforts of at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). UBE2J2 (Ubiquitin-conjugating enzyme E2 J2), also known as NCUBE2 (Non-canonical ubiquitin-conjugating enzyme 2), is a 259 amino acid single pass type IV membrane protein that that belongs to the E2 ubiquitin-conjugating enzyme family and is involved in protein degradation. Localized to the membrane of the endoplasmic reticulum (ER), UBE2J2 catalyzes the attachment of ubiquitin to misfolded membrane proteins, thereby targeting them for proteasomal destruction. This ATP-dependent reaction yields AMP, a diphosphate and a ubiquitin-tagged protein and may be a method of quality control within the ER. Two isoforms of UBE2J2 exist due to alternative splicing events.

    ID gène
    118424
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