APLP2 anticorps (AA 501-600) (Alexa Fluor 350)

N° du produit ABIN1399227

Détail du produit anti-APLP2 anticorps (Alexa Fluor 350)

Antigène: APLP2 (Amyloid beta (A4) Precursor-Like Protein 2 (APLP2))

Épitope: AA 501-600

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp APLP2 est conjugé à/à la Alexa Fluor 350

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Homologie: Human,Mouse,Rat,Pig,Horse,Chicken

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human APLP2

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur APLP2

Antigène: APLP2 (Amyloid beta (A4) Precursor-Like Protein 2 (APLP2))

Autre désignation: APLP2 (APLP2 Produits)

Synonymes: anticorps HAI, anticorps MT-SP1, anticorps MTSP1, anticorps PRSS14, anticorps SNC19, anticorps TADG15, anticorps TMPRSS14, anticorps APLP-2, anticorps APPH, anticorps APPL2, anticorps CDEBP, anticorps AI790698, anticorps Apph, anticorps WALPLP2, anticorps aplp2 B, anticorps APLP2, anticorps si:dkey-11k4.3, anticorps aplp2 A, anticorps MGC86389, anticorps suppression of tumorigenicity 14, anticorps amyloid beta precursor like protein 2, anticorps amyloid beta (A4) precursor-like protein 2, anticorps amyloid beta (A4) precursor-like protein 2 S homeolog, anticorps amyloid beta (A4) precursor-like protein 2 L homeolog, anticorps ST14, anticorps APLP2, anticorps Aplp2, anticorps aplp2.S, anticorps aplp2, anticorps aplp2.L

Sujet:

Synonyms: amyloid beta A4 precursor like protein 2, Amyloid like protein 2, amyloid precursor protein homolog HSD2, Amyloid protein homolog, Amyloid-like protein 2, APLP-2, Aplp2, APLP2_HUMAN, APPH, APPL2, CDEBP, CDEI box binding protein, CDEI box-binding protein.

Background: APLP2 is a human sperm membrane protein which contains a segment with high homology to the transmembrane-cytoplasmic domains of APP found in brain plaques of Alzheimer disease patients. The human amyloid precursor-like protein APLP2 is a highly conserved homolog of a sequence-specific DNA-binding mouse protein with an important function in the cell cycle. The gene which encodes APLP2 maps to human chromosome 11q24.May play a role in the regulation of hemostasis. The soluble form may have inhibitory properties towards coagulation factors. May interact with cellular G-protein signaling pathways. May bind to the DNA 5'-GTCACATG-3'(CDEI box). Inhibits trypsin, chymotrypsin, plasmin, factor XIA and plasma and glandular kallikrein.

ID gène: 334

Pathways: EGFR Signaling Pathway, Transition Metal Ion Homeostasis, Feeding Behaviour