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ELL3 anticorps (AA 51-158) (Alexa Fluor 555)

ELL3 Reactivité: Humain IF (cc), IF (p) Hôte: Lapin Polyclonal Alexa Fluor 555
N° du produit ABIN1399727
  • Antigène Voir toutes ELL3 Anticorps
    ELL3 (Elongation Factor RNA Polymerase II-Like 3 (ELL3))
    Épitope
    • 14
    • 8
    • 8
    • 6
    • 1
    • 1
    • 1
    • 1
    AA 51-158
    Reactivité
    • 33
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 31
    • 2
    Lapin
    Clonalité
    • 33
    Polyclonal
    Conjugué
    • 10
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp ELL3 est conjugé à/à la Alexa Fluor 555
    Application
    • 19
    • 16
    • 12
    • 12
    • 3
    • 3
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Homologie
    Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Chicken,Rabbit
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human ELL3
    Isotype
    IgG
    Top Product
    Discover our top product ELL3 Anticorps primaire
  • Indications d'application
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    ELL3 (Elongation Factor RNA Polymerase II-Like 3 (ELL3))
    Autre désignation
    ELL3 (ELL3 Produits)
    Synonymes
    anticorps DKFZp469F0639, anticorps A930015D22Rik, anticorps elongation factor for RNA polymerase II 3, anticorps elongation factor RNA polymerase II-like 3 L homeolog, anticorps elongation factor RNA polymerase II-like 3, anticorps ELL3, anticorps ell3.L, anticorps Ell3
    Sujet

    Synonyms: B cell translocation gene 2, BTG family member 2, Btg2, BTG2_HUMAN, Nerve growth factor inducible anti prolerative, NGF inducible anti prolerative protein PC3, NGF-inducible anti-prolerative protein PC3, PC3, Pheochromacytoma cell 3, Protein BTG2, TIS21.

    Background: Eukaryotic RNA polymerase II mediates the synthesis of mature and functional messenger RNA. This is a multistep process, called the transcription cycle, that includes five stages: preinitiation, promoter, clearance, elongation and termination. Elongation is thought to be a critical stage for the regulation of gene expression. ELL (11-19 lysine-rich leukemia protein), also designated MEN, functions as an RNA polymerase II elongation factor that increases the rate of transcription by suppressing transient pausing by RNA polymerase II. It is also thought to regulate cellular proliferation. ELL is abundantly expressed in peripheral blood leukocytes, skeletal muscle, placenta and testis, with lower expression in spleen, thymus, heart, brain, lung, kidney, liver and ovary. ELL3 is a 397 amino acid nuclear protein that functions as an RNA polymerase II elongation factor that increases the rate of transcription by suppressing transient pausing by RNA polymerase II. Though similar to ELL and ELL2, ELL3 is exclusively expressed in testis.

    ID gène
    80237
    Pathways
    Negative Regulation of intrinsic apoptotic Signaling
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