C14orf174 anticorps (AbBy Fluor® 350)
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- Antigène Tous les produits C14orf174
- C14orf174 (Chromosome 14 Open Reading Frame 174 (C14orf174))
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Reactivité
- Humain, Rat, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp C14orf174 est conjugé à/à la AbBy Fluor® 350
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Application
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Réactivité croisée
- Humain, Souris, Rat
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human SAMD15/C14orf174
- Isotype
- IgG
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- Indications d'application
- IF(IHC-P) 1:50-200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- C14orf174 (Chromosome 14 Open Reading Frame 174 (C14orf174))
- Autre désignation
- C14orf174 (C14orf174 Produits)
- Synonymes
- anticorps C14orf174, anticorps FAM15A, anticorps Gm263, anticorps sterile alpha motif domain containing 15, anticorps SAMD15, anticorps Samd15
- Sujet
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Synonyms: chromosome 14 open reading frame 174, FAM15A, SAM domain-containing protein 15, SAM15_HUMAN, SAMD15, Sterile alpha mot domain-containing protein 15.
Background: C14orf174, is a 674 amino acid protein that contains one SAM (sterile alpha motif) domain. Existing as two alternatively spliced isoforms,C14orf174 is encoded by a gene that maps to human chromosome 14q24.3. Chromosome 14 contains about 700 genes and 106 million base pairs and makes up about 3.5 % of human cellular DNA. Chromosome 14 encodes the presinilin 1 (PSEN1) gene, which is one of the three key genes associated with the development of Alzheimer's disease. The SERPINA1 gene is located on chromosome 14 and when defective leads to the genetic disorder ?-antitrypsin deficiency. This disorder is characterized by severe lung complications and liver dysfunction. Notably, the immunoglobulin heavy chain locus is found on chromosome 14 and has been identified as a fusion with the chromosome 19 encoded protein Bcl-3 in the (14,19) translocations found in a variety of B cell malignancies.
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