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PARP16 anticorps (AA 120-170) (AbBy Fluor® 488)

PARP16 Reactivité: Humain, Souris, Rat WB, IF (p) Hôte: Lapin Polyclonal AbBy Fluor® 488
N° du produit ABIN1403710
  • Antigène Voir toutes PARP16 Anticorps
    PARP16 (Poly (ADP-Ribose) Polymerase Family, Member 16 (PARP16))
    Épitope
    • 14
    • 8
    • 7
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 120-170
    Reactivité
    • 35
    • 19
    • 19
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 1
    Humain, Souris, Rat
    Hôte
    • 33
    • 2
    Lapin
    Clonalité
    • 34
    • 1
    Polyclonal
    Conjugué
    • 12
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp PARP16 est conjugé à/à la AbBy Fluor® 488
    Application
    • 33
    • 15
    • 14
    • 13
    • 12
    • 5
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
     Réactivité croisée
    Humain, Souris, Rat
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human PARP16
    Isotype
    IgG
    Top Product
    Discover our top product PARP16 Anticorps primaire
  • Indications d'application
    IF(IHC-P) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    PARP16 (Poly (ADP-Ribose) Polymerase Family, Member 16 (PARP16))
    Autre désignation
    PARP16 (PARP16 Produits)
    Synonymes
    anticorps PARP16, anticorps zgc:77744, anticorps ARTD15, anticorps C15orf30, anticorps pART15, anticorps BC055447, anticorps C79952, anticorps PARP-16, anticorps LRRGT00109, anticorps RGD1306243, anticorps poly(ADP-ribose) polymerase family member 16, anticorps poly(ADP-ribose) polymerase family member 16 L homeolog, anticorps poly (ADP-ribose) polymerase family, member 16, anticorps PARP16, anticorps parp16.L, anticorps parp16, anticorps Parp16
    Sujet

    Synonyms: C15orf30, Chromosome 15 open reading frame 30, EC 2.4.2.30, FLJ25281, PAR16_HUMAN, PARP 16, PARP-16, Parp16, Poly ADP ribose polymerase family member 16, Poly [ADP ribose] polymerase 16, Poly [ADP-ribose] polymerase 16.

    Background: Poly(ADP-ribosylation) is a method of DNA damage-dependent posttranslational modification that helps to rescue injured proliferating cells from cell death. The PARP (poly(ADP-ribose) polymerase) proteins comprise a superfamily of enzymes that functionally modify histones and other nuclear proteins, thereby preventing cell death. PARPs use NAD+ as a substrate to catalytically transfer ADP-ribose residues onto protein acceptors, a process that, when repeated multiple times, leads to the formation of poly(ADPribose) chains on the protein. The presence of these chains alters the function of the target protein and promotes cell survival. PARP proteins are implicated in a variety of diseases, including cancer, neurodegenerative and inflammatory disorders. PARP-16 is a 322 amino acid poly (ADP-ribose) polymerase protein localized to the membrane. Expressed as three isoforms produced by alternative splicing, PARP-16 contains one PARP catalytic domain.

    ID gène
    54956
    UniProt
    Q8N5Y8
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