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TEFM anticorps (AA 60-110) (Biotin)

TEFM Reactivité: Humain, Souris, Rat WB, IHC (p) Hôte: Lapin Polyclonal Biotin
N° du produit ABIN1403809
  • Antigène Voir toutes TEFM Anticorps
    TEFM (Transcription Elongation Factor, Mitochondrial (TEFM))
    Épitope
    • 14
    • 4
    • 2
    • 1
    • 1
    AA 60-110
    Reactivité
    • 23
    • 15
    • 15
    • 2
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 23
    Lapin
    Clonalité
    • 23
    Polyclonal
    Conjugué
    • 7
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp TEFM est conjugé à/à la Biotin
    Application
    • 18
    • 13
    • 3
    • 3
    • 2
    • 2
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
     Réactivité croisée
    Humain, Souris, Rat
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human C17orf42
    Isotype
    IgG
    Top Product
    Discover our top product TEFM Anticorps primaire
  • Indications d'application
    WB 1:300-5000
    IHC-P 1:200-400
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C for 12 months.
    Date de péremption
    12 months
  • Antigène
    TEFM (Transcription Elongation Factor, Mitochondrial (TEFM))
    Autre désignation
    C17orf42 (TEFM Produits)
    Synonymes
    anticorps C17orf42, anticorps TEFM, anticorps zgc:153083, anticorps RGD1306595, anticorps transcription elongation factor, mitochondrial, anticorps TEFM, anticorps tefm, anticorps Tefm
    Sujet

    Synonyms: Chromosome 17 open reading frame 42, FLJ22729, Hypothetical protein LOC79736, MGC24674, UPF0629 protein C17orf42, TEFM_HUMAN, TEFM, transcription elongation factor, mitochondrial,

    Background: C17orf42 is a 360 amino acid protein that exists as two alternatively spliced isoforms and is encoded by a gene mapping to human chromosome 17. Chromosome 17 makes up over 2.5 % of the human genome with about 81 million bases encoding over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair, specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes. Chromosome 17 is also linked to neurofibromatosis, a condition characterized by neural and epidermal lesions, and dysregulated Schwann cell growth. Alexander disease, Birt-Hogg-Dube syndrome and Canavan disease are also associated with chromosome 17.

    ID gène
    79736
    UniProt
    Q96QE5
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