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ABCA7 anticorps (AA 251-350) (Cy5.5)

ABCA7 Reactivité: Humain FACS, IF (cc), IF (p) Hôte: Lapin Polyclonal Cy5.5
N° du produit ABIN1407641
  • Antigène Voir toutes ABCA7 Anticorps
    ABCA7 (ATP-Binding Cassette, Sub-Family A (ABC1), Member 7 (ABCA7))
    Épitope
    • 15
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 251-350
    Reactivité
    • 24
    • 8
    • 6
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 25
    • 1
    Lapin
    Clonalité
    • 25
    • 1
    Polyclonal
    Conjugué
    • 9
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp ABCA7 est conjugé à/à la Cy5.5
    Application
    • 17
    • 12
    • 12
    • 7
    • 6
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
     Réactivité croisée
    Humain
    Homologie
    Mouse,Rat
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human ABCA7
    Isotype
    IgG
    Top Product
    Discover our top product ABCA7 Anticorps primaire
  • Indications d'application
    FCM 1:20-100
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    ABCA7 (ATP-Binding Cassette, Sub-Family A (ABC1), Member 7 (ABCA7))
    Autre désignation
    ABCA7 (ABCA7 Produits)
    Synonymes
    anticorps ABCX, anticorps Abc51, anticorps ABCA-SSN, anticorps ABCA7, anticorps ATP-binding cassette, sub-family A (ABC1), member 7, anticorps ATP binding cassette subfamily A member 7, anticorps ATP-binding cassette sub-family A member 7, anticorps Abca7, anticorps ABCA7, anticorps LOC100088822
    Sujet

    Synonyms: ABC transporter ABCA7, ABC transporter member 7, ABCA SSN, ABCX, ATP binding cassette sub family A ABC1 member 7, ATP binding cassette sub family A member 7, ATP binding Cassette Transporter A7,FLJ40025, Macrophage ABC transporter, ABCA7_HUMAN.

    Background: ATP-binding cassette (ABC) transporters are an evolutionarily conserved family of widely-expressed proteins that use ATP hydrolysis to catalyze the transport of various molecules across extracellular and intracellular membranes. Eukaryotic ABC transporters are largely responsible for trafficking hydrophobic compounds either within the cell as part of a metabolic process, outside the cell for transport to other organs, or for secretion from the body. The cholesterol-responsive transporter, ABCA7, maps to human chromosome 19 and mouse chromosome 10 and has been reported as a candidate regulator of ceramide transport in epidermal lipid reorganization. High expression levels of ABCA7 have been reported in myelolymphatic tissues, reticuloendothelial cells, peripheral leukocytes, thymus, spleen and bone marrow. This expression pattern of the two alternatively-spliced isoforms also indicates an involvement in lipid homeostasis in cells of the immune system, though the complete role of ABCA7 is not yet known. Full-length type I ABCA7 has shown plasma membrane localization, while the type II splicing variant has shown expression predominantly in the endoplasmic reticulum.

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