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RIC8A anticorps (AA 301-400) (Cy5.5)

RIC8A Reactivité: Humain WB, IF (cc), IF (p) Hôte: Lapin Polyclonal Cy5.5
N° du produit ABIN1408673
  • Antigène Voir toutes RIC8A Anticorps
    RIC8A (Resistance To Inhibitors of Cholinesterase 8 Homolog A (C. Elegans) (RIC8A))
    Épitope
    • 14
    • 7
    • 6
    • 6
    • 6
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 301-400
    Reactivité
    • 51
    • 16
    • 13
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    Humain
    Hôte
    • 49
    • 1
    • 1
    Lapin
    Clonalité
    • 50
    • 1
    Polyclonal
    Conjugué
    • 19
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp RIC8A est conjugé à/à la Cy5.5
    Application
    • 41
    • 22
    • 12
    • 12
    • 5
    • 5
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Homologie
    Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human RIC8A
    Isotype
    IgG
    Top Product
    Discover our top product RIC8A Anticorps primaire
  • Indications d'application
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    RIC8A (Resistance To Inhibitors of Cholinesterase 8 Homolog A (C. Elegans) (RIC8A))
    Autre désignation
    RIC8A (RIC8A Produits)
    Synonymes
    anticorps RIC8, anticorps AI114950, anticorps RIC-8, anticorps Ric8a, anticorps Ric-8A, anticorps Ric8, anticorps ric-8, anticorps ric8, anticorps synembryn, anticorps xtric-8, anticorps zgc:92294, anticorps Syn, anticorps ric8a, anticorps ric8ab, anticorps CG15797, anticorps DmRic8, anticorps Dmel\\CG15797, anticorps Ric-8, anticorps l(1)G0397, anticorps ric-8a, anticorps ricc8aa, anticorps fj97c10, anticorps synbl, anticorps wu:fj97c10, anticorps RIC8 guanine nucleotide exchange factor A, anticorps microRNA 6743, anticorps synembryn-A, anticorps RIC8 guanine nucleotide exchange factor A L homeolog, anticorps CG15797 gene product from transcript CG15797-RB, anticorps synembryn, anticorps RIC8 guanine nucleotide exchange factor A S homeolog, anticorps Synembryn, anticorps RIC8 guanine nucleotide exchange factor B, anticorps RIC8A, anticorps Ric8a, anticorps ric8a, anticorps MIR6743, anticorps Tsp_08768, anticorps ric8a.L, anticorps LOC411841, anticorps ric8a.S, anticorps ric-8, anticorps ric8b
    Sujet

    Synonyms: Protein Ric-8A, resistance to inhibitors of cholinesterase 8 homolog A C. elegans, RIC8, RIC8A, RIC8A_HUMAN, synembryn, Synembryn-A, MGC104517, MGC131931, MGC148073, MGC148074.

    Background: The Ras superfamily of GTPases can be subdivided into the Ras, Rho/Rac, Sar, Rab, Arf, Rap and Ran subfamilies, all of which control multiple aspects of cell function, including cytoskeletal rearrangement, nuclear signaling and cell growth. The Ras superfamily of GTPases function as regulated switches that toggle between a biologically active GTP-bound and an inactive GDP-bound form. This activation is catalyzed by guanine nucleotide exchange factors (GEFs). RIC-8A (resistance to inhibitors of cholinesterase 8 homolog A), also known as RIC8 or Synembryn-A, is a 530 amino acid cytoplasmic protein that can activate several G-alpha proteins, including G?i-1, G?q and G?o. Functioning as a guanine nucleotide exchange factor, RIC-8A binds to GDP-associated substrates and exchanges bound GDP for free GTP. Via its ability to stimulate protein function, RIC-8A plays a role in regulating mitotic movement and may be involved in receptor-mediated ERK activation. RIC-8A is expressed as three isoforms due to alternative splicing events.

    Pathways
    Regulation of G-Protein Coupled Receptor Protein Signaling, Feeding Behaviour, Asymmetric Protein Localization
Support technique