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PQBP1 anticorps (AA 185-265) (Cy5.5)

PQBP1 Reactivité: Humain WB, IF (cc), IF (p) Hôte: Lapin Polyclonal Cy5.5
N° du produit ABIN1411001
  • Antigène Voir toutes PQBP1 Anticorps
    PQBP1 (Polyglutamine Binding Protein 1 (PQBP1))
    Épitope
    • 14
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    AA 185-265
    Reactivité
    • 34
    • 9
    • 7
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 2
    • 1
    Humain
    Hôte
    • 32
    • 3
    Lapin
    Clonalité
    • 32
    • 3
    Polyclonal
    Conjugué
    • 18
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp PQBP1 est conjugé à/à la Cy5.5
    Application
    • 29
    • 12
    • 12
    • 11
    • 7
    • 7
    • 4
    • 4
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Homologie
    Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human PQBP1
    Isotype
    IgG
    Top Product
    Discover our top product PQBP1 Anticorps primaire
  • Indications d'application
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    PQBP1 (Polyglutamine Binding Protein 1 (PQBP1))
    Autre désignation
    PQBP1 (PQBP1 Produits)
    Synonymes
    anticorps PQBP1, anticorps MRX55, anticorps MRXS3, anticorps MRXS8, anticorps NPW38, anticorps RENS1, anticorps SHS, anticorps PQBP-1, anticorps Sfc2, anticorps npw38, anticorps polyglutamine binding protein 1, anticorps PQBP1, anticorps Pqbp1
    Sujet

    Synonyms: 38 kDa nuclear protein containing a WW domain, Mental retardation, X linked 55, MRX55, MRXS3, MRXS8, Npw38, Nuclear protein containing WW domain 38 kD, Polyglutamine binding protein 1, Polyglutamine tract binding protein 1, Polyglutamine tract-binding protein 1, Polyglutamine-binding protein 1, PQBP 1, PQBP-1, PQBP1, PQBP1_HUMAN, RENS1, SHS, Sutherland Haan X linked mental retardation syndrome.

    Background: Polyglutamine(Q) tract binding protein-1 (PQBP-1) is a transcription repressor that associates with polyglutamine tract-containing transcription regulators and causative genes for neurodegenerative disorders. Hepta- and di-amino acid repeat sequences rich in polar residues are essential for PQBP-1 to interact with polyglutamine tract-containing proteins (i.e. huntingtin, androgen receptor and Brain-2). PQBP-1 contains a WWP/WW domain that binds proline-rich motifs and a C2 domain that can influence Ca2+-dependent phospholipid signaling. PQBP-1 localizes to the nucleus and is present in neurons throughout the brain, with abundant levels in hippocampus, cerebellar cortex and olfactory bulb. The human PQBP-1 gene maps to chromosome Xp11.23.

    Pathways
    Ribonucleoprotein Complex Subunit Organization
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