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PANK3 anticorps (AA 271-370) (HRP)

PANK3 Reactivité: Rat WB, ELISA, IHC (p), IHC (fro) Hôte: Lapin Polyclonal HRP
N° du produit ABIN1416382
  • Antigène Voir toutes PANK3 Anticorps
    PANK3 (Pantothenate Kinase 3 (PANK3))
    Épitope
    • 14
    • 8
    • 7
    • 7
    • 3
    • 1
    • 1
    AA 271-370
    Reactivité
    • 29
    • 15
    • 1
    Rat
    Hôte
    • 38
    • 5
    Lapin
    Clonalité
    • 40
    • 3
    Polyclonal
    Conjugué
    • 15
    • 4
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp PANK3 est conjugé à/à la HRP
    Application
    • 43
    • 25
    • 19
    • 13
    • 13
    • 5
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
     Réactivité croisée
    Rat
    Homologie
    Human,Mouse,Dog,Cow,Sheep,Pig,Horse,Chicken
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human PANK3
    Isotype
    IgG
    Top Product
    Discover our top product PANK3 Anticorps primaire
  • Indications d'application
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Conseil sur la manipulation
    Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    PANK3 (Pantothenate Kinase 3 (PANK3))
    Autre désignation
    PANK3 (PANK3 Produits)
    Synonymes
    anticorps MGC84572, anticorps pantothenate kinase 3, anticorps pantothenate kinase 3 S homeolog, anticorps PANK3, anticorps Pank3, anticorps pank3.S, anticorps pank3
    Sujet

    Synonyms: hPanK3, MGC16863, OTTHUMP00000160961, Pank3, PANK3_HUMAN, Pantothenate kinase 3, pantothenic acid kinase, Pantothenic acid kinase 3.

    Background: The pantothenate kinase (PANK) family of proteins catalyzes the first step in coenzyme A (CoA) biosynthesis. Coenzyme A is an important coenzyme involved in the synthesis and oxidation of fatty acids, as well as the oxidation of pyruvate in the citric acid (Krebs) cycle. Pantothenate kinase 3 (PANK3) is a 370 amino acid member of the pantothenate kinase family that plays a role in the physiological regulation of the intracellular CoA concentration. Localized to the cytoplasm, PANK3 is regulated by feedback inhibition by CoA and its thioesters. PANK3 transfers a phosphate from ATP to pantothenate (Vitamin B5), resulting in formation of 4?-phosphopantothenate. Closely related to its family members, PANK1, PANK2 and PANK4, PANK3 is highly expressed in liver. Pantothenate kinase associated neurodegeneration (PKAN) results from mutations in the gene encoding PANK2, the only mitochondria targeted human PANK.

    ID gène
    79646
    Pathways
    Ribonucleoside Biosynthetic Process
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