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MLLT11 anticorps (AA 41-90) (Cy5.5)

MLLT11 Reactivité: Humain IF (cc), IF (p) Hôte: Lapin Polyclonal Cy5.5
N° du produit ABIN1417609
  • Antigène Voir toutes MLLT11 Anticorps
    MLLT11 (Myeloid/lymphoid Or Mixed-Lineage Leukemia (Trithorax Homolog), Translocated To, 11 (MLLT11))
    Épitope
    • 14
    • 6
    • 1
    • 1
    • 1
    AA 41-90
    Reactivité
    • 23
    • 3
    • 2
    Humain
    Hôte
    • 22
    • 2
    Lapin
    Clonalité
    • 22
    • 2
    Polyclonal
    Conjugué
    • 7
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp MLLT11 est conjugé à/à la Cy5.5
    Application
    • 12
    • 12
    • 10
    • 4
    • 3
    • 3
    • 2
    • 2
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
     Réactivité croisée
    Humain
    Homologie
    Mouse,Rat,Dog,Cow,Pig,Horse,Rabbit
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human MLLT11
    Isotype
    IgG
    Top Product
    Discover our top product MLLT11 Anticorps primaire
  • Indications d'application
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    MLLT11 (Myeloid/lymphoid Or Mixed-Lineage Leukemia (Trithorax Homolog), Translocated To, 11 (MLLT11))
    Autre désignation
    MLLT11 (MLLT11 Produits)
    Synonymes
    anticorps AF1Q, anticorps RP11-316M1.10, anticorps AI839562, anticorps Af1q, anticorps Zfp692, anticorps RGD1305525, anticorps fc23g02, anticorps si:ch211-210h11.4, anticorps wu:fc23g02, anticorps myeloid/lymphoid or mixed-lineage leukemia; translocated to, 11, anticorps MLLT11, transcription factor 7 cofactor, anticorps MLLT11, anticorps Mllt11, anticorps mllt11
    Sujet

    Synonyms: AF1Q, ALL1 fused gene from chromosome 1q, MLLT 11, MLLT-11, Myeloid/lymphoid or mixed lineage leukemia trithorax homolog, Drosophila translocated to 11, Protein AF1q, RP11 316M1.10.

    Background: The gene encoding the Mixed-Lineage Leukemia (MLL) proteins is located on chromosome 11q23. Chromosomal translocations involving band 11q23 result in rogue activator proteins that are associated with approximately 10 % of patients with acute lymphoblastic leukemia (ALL) and 5 % of patients with acute myeloid leukemia (AML). Most patients affected are less than 1 year of age. MLLT11, also known as mixed-lineage leukemia translocated to 11 or AF1q, is a 90 amino acid MLL fusion partner. Based on the expression patterns of MLLT11, it is thought that MLLT11 plays a role in leukemogenesis and, specifically, the progression of acute monocytic leukemia (AML). Also, expressed in embryonic brain cortex, MLLT11 is upregulated during neuronal differentiation and is thought to play a role in the development of the central nervous system. Finally, MLLT11 has been shown to be differentially expressed in highly metastatic cells, in comparison with non-metastatic parent cells. Such findings suggest a role of MLLT11 in tumorigenesis.

    ID gène
    10962
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