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INTS3 anticorps (AA 960-998) (Cy3)

INTS3 Reactivité: Humain, Souris, Rat WB, IF (p) Hôte: Lapin Polyclonal Cy3
N° du produit ABIN1422407
  • Antigène Voir toutes INTS3 Anticorps
    INTS3 (Integrator Complex Subunit 3 (INTS3))
    Épitope
    • 14
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 960-998
    Reactivité
    • 28
    • 19
    • 17
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 28
    Lapin
    Clonalité
    • 28
    Polyclonal
    Conjugué
    • 11
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp INTS3 est conjugé à/à la Cy3
    Application
    • 24
    • 12
    • 6
    • 5
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
     Réactivité croisée
    Humain, Souris, Rat
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human INTS3
    Isotype
    IgG
    Top Product
    Discover our top product INTS3 Anticorps primaire
  • Indications d'application
    IF(IHC-P) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    INTS3 (Integrator Complex Subunit 3 (INTS3))
    Autre désignation
    INTS3 (INTS3 Produits)
    Synonymes
    anticorps INTS3, anticorps Ints3, anticorps NV18802, anticorps ACYPI009450, anticorps DL3335W, anticorps FCAALL.260, anticorps embryo defective 2739, anticorps C1orf193, anticorps C1orf60, anticorps INT3, anticorps SOSS-A, anticorps C77668, anticorps RGD1304593, anticorps si:dkey-27c15.2, anticorps integrator complex subunit 3, anticorps integrator complex subunit 3 L homeolog, anticorps embryo defective 2739, anticorps INTS3, anticorps ints3.L, anticorps CpipJ_CPIJ008133, anticorps ints3, anticorps Ints3, anticorps LOC100168776, anticorps emb2739
    Sujet

    Synonyms: INT3, SOSSA, SOSS-A, C1orf60, C1orf193, Integrator complex subunit 3, SOSS complex subunit A, Sensor of single-strand DNA complex subunit A, Sensor of ssDNA subunit A, INTS3

    Background: Component of the Integrator complex. The Integrator complex is involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes. Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. The SOSS complex associates with single-stranded DNA at DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability. The SOSS complex is required for efficient homologous recombination-dependent repair of double-strand breaks (DSBs) and ATM-dependent signaling pathways. In the SOSS complex, it is required for the assembly of the complex and for stabilization of the complex at DNA damage sites.

    ID gène
    65123
    UniProt
    Q68E01
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