CD52 anticorps
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- Antigène Voir toutes CD52 Anticorps
- CD52
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Reactivité
- Souris
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Hôte
- Rat
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp CD52 est non-conjugé
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Application
- Flow Cytometry (FACS), Immunoprecipitation (IP)
- Specificité
- This antibody reacts with mouse CAMPATH-1/CD52.
- Purification
- Protein G agarose
- Immunogène
- Mouse IL-2R alpha-TGM splenocyte
- Clone
- BTG-2G
- Isotype
- IgG2a
- Top Product
- Discover our top product CD52 Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- PBS containing 50 % glycerol, pH 7.2. Contains no preservatives.
- Agent conservateur
- Without preservative
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- -20 °C
- Stockage commentaire
- Upon receipt, store (in aliqouts) at -20 °C.
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- Antigène
- CD52
- Autre désignation
- CD52 / CAMPATH-1 (CD52 Produits)
- Synonymes
- anticorps CD52, anticorps AI463198, anticorps B7, anticorps B7-Ag, anticorps CAMPATH-1, anticorps CLS1, anticorps MB7, anticorps CDW52, anticorps CE5, anticorps CD52 molecule, anticorps CD52 antigen, anticorps CD52, anticorps Cd52
- Sujet
- CAMPATH-1, also known as CD52, is a heavily glycosylated, GPI-anchored protein expressed at high levels on almost all thymocytes, lymphocytes, monocytes, and macrophages. The function of CD52 is unknown. However, CD52 is an exceptionally good target for complement-mediated cell lysis and antibody-mediated cellular cytotoxicity. Humanized CAMPATH-1antibodies have been used therapeutically to effectively deplete lymphocytes in allogeneic bone marrow transplants, hematologic malignancies, and autoimmune diseases. Clinical trials suggest CAMPATH-1 antibodies are especially promising in the treatment of leukemia, non-Hodgkin lymphomas, and rheumatoid arthritis. The apparent size of CAMPATH-1 by SDS-PAGE is 25-29 kDa, however, the actual molecule is much smaller, ~ 8-9 kDa as confirmed by total structure analysis and mass spectrometry.Synonyms: CDw52, Cambridge pathology 1 antigen, Epididymal secretory protein E5, HE5
- ID gène
- 23833
- NCBI Accession
- NP_038734
- UniProt
- Q64389
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