Glypican 3 anticorps (Middle Region)
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- Antigène Voir toutes Glypican 3 (GPC3) Anticorps
- Glypican 3 (GPC3)
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Épitope
- AA 345-370, Middle Region
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp Glypican 3 est non-conjugé
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Application
- Immunofluorescence (IF), Enzyme Immunoassay (EIA)
- Specificité
- This antibody recognizes Human and Mouse Glypican 3 (GPC3). Other species not tested.
- Purification
- Protein G Column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
- Immunogène
- KLH conjugated synthetic peptide selected from the center region of Human GPC3 (aa 345-370)
- Isotype
- Ig Fraction
- Top Product
- Discover our top product GPC3 Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25 mg/mL
- Buffer
- PBS containing 0.09 % (W/V) Sodium Azide as preservative
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- Antigène
- Glypican 3 (GPC3)
- Autre désignation
- Glypican-3 / GPC3 (GPC3 Produits)
- Synonymes
- anticorps GPC3, anticorps sgb, anticorps dgsx, anticorps sdys, anticorps sgbs, anticorps oci-5, anticorps sgbs1, anticorps DGSX, anticorps GTR2-2, anticorps MXR7, anticorps OCI-5, anticorps SDYS, anticorps SGB, anticorps SGBS, anticorps SGBS1, anticorps Glypican-3, anticorps glypican 3, anticorps gpc3, anticorps GPC3, anticorps Gpc3
- Sujet
- GPC3 is a cell surface proteoglycan that bears heparan sulfate. This protein may be involved in the suppression/modulation of growth in the predominantly mesodermal tissues and organs, and may play a role in the modulation of IGF2 interactions with its receptor and thereby modulate its function. Members of the glypican-related integral membrane proteoglycan family contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol (GPI) linkage. These proteins may play a role in the control of cell division, growth regulation, and tumor predisposition. Deletion mutations in GPC3 are the cause of Simpson-Golabi-Behmel syndrome (SGBS), also known as Simpson dysmorphia syndrome (SDYS). SGBS is a condition characterized by pre- and postnatal overgrowth (gigantism) with visceral and skeletal anomalies.Synonyms: GTR2-2, Intestinal protein OCI-5, MXR7, OCI5
- ID gène
- 2719, 9606
- UniProt
- P51654
- Pathways
- Glycosaminoglycan Metabolic Process
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